Evidence map›Paper›PMID 28124139›Full record

ArticleInternational archives of occupational and environmental health2017

Biomarkers of endothelial activation and thrombosis in tunnel construction workers exposed to airborne contaminants.

Dag G Ellingsen, Ingebjørg Seljeflot, Yngvar Thomassen, Magny Thomassen, Berit Bakke, Bente Ulvestad

Abstract read
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In one paragraph

Article in International archives of occupational and environmental health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. A study of atherothrombotic biomarkers in welders.International archives of occupational and environmental health · 2019
    Article
  2. Viruses and non-allergen environmental triggers in asthma.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Dag G EllingsenNational Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway. dag.ellingsen@stami.no.
Ingebjørg SeljeflotCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Norway.
Yngvar ThomassenNational Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway.
Magny ThomassenNorwegian University of Life Sciences, Ås, Norway.
Berit BakkeNational Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway.
Bente UlvestadNational Institute of Occupational Health, P.O. Box 8149 Dep, 0033, Oslo, Norway.
National Institute of Occupational Health · NONorwegian University of Life Sciences · NOOslo University Hospital · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aims were to study biomarkers of systemic inflammation, platelet/endothelial activation and thrombosis in tunnel construction workers (TCW).

methodsBiomarkers and blood fatty acids were measured in blood of 90 TCW and 50 referents before (baseline) and towards the end (follow-up) of a 12 days work period. They had been absent from work for 9 days at baseline. Air samples were collected by personal sampling.

resultsPersonal thoracic air samples showed geometric mean (GM) particulate matter and α-quartz concentrations of 604 and 74 µg/m

conclusionsTCW had slightly reduced systemic inflammation and platelet activation although highly exposed to particulate matter, α-quarz and diesel exhaust, which might be due to increased physical activity during the exposure period. The slightly increased ICAM-1 may indicate monocyte recruitment to the lungs. The diet was substantially altered towards a less beneficial fatty acid profile.

Indexed as

Construction IndustryAdolescentAdultBiomarkersCarbonCD40 LigandFatty AcidsHumansIntercellular Adhesion Molecule-1MaleMiddle AgedNorwayOccupational ExposureParticulate MatterPlatelet ActivationP-SelectinBiomarkersCarbonCD40 LigandFatty AcidsIntercellular Adhesion Molecule-1Particulate MatterP-SelectinQuartzTumor Necrosis Factor-alphaVehicle EmissionsCardiovascular diseaseFatty acidsP-selectinTNF-α

Identifiers

PMID28124139
OpenAlexW2581882741

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.