Evidence mapPaperPMID 28124651Full record

ReviewAmerican journal of rhinology & allergy2016

Aspirin-exacerbated respiratory disease: Prevalence, diagnosis, treatment, and considerations for the future.

Joshua L Kennedy, Ashley N Stoner, Larry Borish

Open access · greenAbstract readReview
In one paragraph

Review in American journal of rhinology & allergy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 74 citations in OpenAlex.

  1. Retinoic acid promotes fibrinolysis and may regulate polyp formation.The Journal of allergy and clinical immunology · 2022
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Differences in men and women suffering from CRSwNP and AERD in quality of life.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Aspirin as a Potential Geroprotector: Experimental Data and Clinical Evidence.Advances in experimental medicine and biology · 2021
    Article
  12. Article
  13. Endoscopic sinus surgery and aspirin desensitization improve otologic-specific SNOT-22 scores.World journal of otorhinolaryngology - head and neck surgery · 2020
    Article
  14. Aspirin-exacerbated respiratory disease: A review.Laryngoscope investigative otolaryngology · 2020
    Review
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Depression symptoms and quality of life among individuals with aspirin-exacerbated respiratory disease.The Journal of asthma : official journal of the Association for the Care of Asthma · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Joshua L KennedyDepartment of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
Ashley N Stoner
Larry Borish
Arkansas Children's Hospital · USUniversity of Arkansas for Medical Sciences · USUniversity of Virginia Health System · US

Funding

INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · 1995 to 2025
$2.5M
NCATS NIH HHS KL2 TR000063NCATS NIH HHS UL1 TR000039NIAID NIH HHS K08 AI121345NIAID NIH HHS R56 AI120055NIAID NIH HHS T32 AI007496NIAID NIH HHS U01 AI100799NIGMS NIH HHS P20 GM103625
6 · The paper itself

Abstract

Aspirin-exacerbated respiratory disease (AERD) is a late onset condition characterized by the Samter triad (aspirin sensitivity [as well as sensitivity to any nonselective cyclooxygenase inhibitor], nasal polyps, asthma) and additional features, including eosinophilic chronic rhinosinusitis, hypereosinophilia, anosmia, frequent absence of atopy, and, intolerance to ingestion of red wine and other alcoholic beverages. The diagnosis is rare, and, because of this, it is also often missed by physicians. However, it is highly overexpressed in patients with severe asthma (and severe chronic rhinosinusitis with nasal polyps), which makes its recognition essential. For this review, we considered mechanisms involved in the pathogenesis of this disease and discussed the clinical symptoms of AERD. We also discussed the role of aspirin desensitization in the treatment of AERD. Also, we considered medications (e.g, leukotriene modifiers) and surgical interventions that have a role in the treatment of AERD.

Indexed as

AnimalsAnti-Allergic AgentsAspirinAsthmaDesensitization, ImmunologicDiagnosis, DifferentialDrug HypersensitivityHumansKetorolacLeukotrienesPrevalenceUnited StatesAnti-Allergic AgentsAspirinKetorolacLeukotrienes

Identifiers

PMID28124651
PMCPMC5108840
OpenAlexW2551655066

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.