Evidence map›Paper›PMID 28137700›Full record

ArticleRespiratory physiology & neurobiology2017

Effects on breathing of agonists to μ-opioid or GABA

Thomas M Langer, Suzanne E Neumueller, Emma Crumley, Nicholas J Burgraff, Sawan Talwar, Matthew R Hodges, Lawrence Pan, Hubert V Forster

Abstract read
In one paragraph

Article in Respiratory physiology & neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Roles of peripheral and central µAmerican journal of physiology. Lung cellular and molecular physiology · 2025
    Article
  2. Article
  3. Sudden Death Induced by Acute Inhalation of Aerosolized Carfentanil.Archives of clinical and biomedical research · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Dynamic Rhythmogenic Network States Drive Differential Opioid Responses in theThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Thomas M LangerDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Suzanne E NeumuellerDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Emma CrumleyDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Nicholas J BurgraffDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Sawan TalwarDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Matthew R HodgesDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
Lawrence PanDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States; Department of Physical Therapy, Marquette University, Milwaukee, WI 53226, United States.
Hubert V ForsterDepartment of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States; Neuroscience Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, United States; Zablocki Veterans Affairs Medical Center, Milwaukee, WI 53226, United States. Electronic address: bforster@mcw.edu.
Medical College of Wisconsin · USMarquette University · USMilwaukee VA Medical Center · US

Funding

INTEGRATED PHYSIOLOGY TRAINING--MOLECULE TO ORGANISMT32HL007852 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Matthew Robert Hodges · 1996 to 2026
$6.5M
Progressive seizure-induced cardiorespiratory dysfunction in a novel mutant rat model of seizure disorderR01HL122358 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI HODGES, MATTHEW ROBERT · 2015 to 2024
$4.3M
MECHANISM(S) OF HYPERNEA ELICITED BY CO2 INHALATIONR01HL025739 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI FORSTER, HUBERT V · 1985 to 2010
$1.8M
Interdependence among neuromodulators of ventilatory controlR01HL112996 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI FORSTER, HUBERT V · 2013 to 2016
$1.5M
NHLBI NIH HHS R01 HL025739NHLBI NIH HHS R01 HL112996NHLBI NIH HHS R01 HL122358NHLBI NIH HHS T32 HL007852
6 · The paper itself

Abstract

Pulmonary ventilation (V̇

Indexed as

Analgesics, OpioidAnimalsDialysisDose-Response Relationship, DrugEnkephalin, Ala(2)-MePhe(4)-Gly(5)-FemaleFunctional LateralityGABA-A Receptor AgonistsGoatsMuscimolNeurotransmitter AgentsRespirationRespiratory CenterSleepWakefulnessAnalgesics, OpioidEnkephalin, Ala(2)-MePhe(4)-Gly(5)-GABA-A Receptor AgonistsMuscimolNeurotransmitter AgentsBreathingGABA(A)NeuromodulationSleepVentral respiratory columnμ-Opioids

Identifiers

PMID28137700
PMCPMC5996971
OpenAlexW2582839955

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.