Evidence map›Paper›PMID 28140456›Full record

ArticleCancer2017

Discussing molecular testing in oncology care: Comparing patient and physician information preferences.

Ana P M Pinheiro, Rachel H Pocock, Jeffrey M Switchenko, Margie D Dixon, Walid L Shaib, Suresh S Ramalingam, Rebecca D Pentz

Abstract read
In one paragraph

Article in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Review
  8. Article
  9. How to identify, incorporate and report patient preferences in clinical guidelines: A scoping review.Health expectations : an international journal of public participation in health care and health policy · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ana P M PinheiroDepartment of Hematology and Oncology, Winship Cancer Institute, Atlanta, Georgia.
Rachel H PocockEmory University School of Medicine, Atlanta, Georgia.
Jeffrey M SwitchenkoRollins School of Public Health, Emory University, Atlanta, Georgia.
Margie D DixonDepartment of Hematology and Oncology, Winship Cancer Institute, Atlanta, Georgia.
Walid L ShaibDepartment of Hematology and Oncology, Winship Cancer Institute, Atlanta, Georgia.
Suresh S RamalingamDepartment of Hematology and Oncology, Winship Cancer Institute, Atlanta, Georgia.
Rebecca D PentzDepartment of Hematology and Oncology, Winship Cancer Institute, Atlanta, Georgia.

Funding

Winship Cancer Institute Cancer Center Support GrantP30CA138292 · NCI · EMORY UNIVERSITY · PI Suresh S Ramalingam · 2009 to 2026
$47.5M
NCI NIH HHS P30 CA138292
6 · The paper itself

Abstract

backgroundMolecular testing to inform treatment and clinical trial choices is now the standard of care for several types of cancer. However, no established guidelines exist for the type of information physicians should cover during discussions with the patient about the test or its results. The objectives of this study were to identify physician and patient preferences regarding information and who should communicate this information and how to inform guidelines for these conversations.

methodsPhysicians and patients who participated in discussions regarding molecular testing were asked to choose 8 topics of most relevance out of a list of 18. The McNemar test was used to determine their top preferences. Patients were asked to identify what information they wanted to receive and who should inform them, and physicians were asked to identify the best aid to communication.

resultsSixty-six patients identified 12 preferred topics: the benefits of testing (88%), how testing determines treatment (88%), implications for family (71%), whether a test indicates the seriousness of disease (68%), purpose of the test (64%), incidental findings (56%), explanation of cancer genetics (53%), how the test is done (46%), limitations (44%), explanation of biomarker (42%), risks (42%), and uninformative results (38%). Physicians added cost (59%). Patients preferred receiving information about molecular testing from their nurse or physician (85%), and physicians preferred using a pamphlet (67%) to augment communication.

conclusionsThe topics identified as important to discuss can inform future guidelines and can contribute to effective communication regarding molecular testing. Cancer 2017;123:1610-1616. © 2017 American Cancer Society.

Indexed as

CommunicationMolecular Diagnostic TechniquesOncologistsPatient PreferencePhysician-Patient RelationsBiomarkers, TumorFemaleHumansMaleMiddle AgedMolecular Targeted TherapyNeoplasmsBiomarkers, Tumorcommunicationinformed consentmolecular testingpatient preference

Identifiers

PMID28140456
PMCPMC5400669

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.