Evidence map›Paper›PMID 28144335›Full record

ReviewBeilstein journal of organic chemistry2016

Interactions between cyclodextrins and cellular components: Towards greener medical applications?

Loïc Leclercq

Open access · diamondAbstract readReview
In one paragraph

Review in Beilstein journal of organic chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 66 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. The Impact of Cyclodextrins on the Physiology ofMolecules (Basel, Switzerland) · 2024
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Cyclodextrins in the antiviral therapy.Journal of drug delivery science and technology · 2021
    Review
  14. Investigation of Vitamin DChembiochem : a European journal of chemical biology · 2021
    Article
  15. Article
  16. Article
  17. How to improve the chemical disinfection of contaminated surfaces by viruses, bacteria and fungus?European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences · 2020
    Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Loïc LeclercqUniv. Lille, CNRS, ENSCL, UMR 8181 - UCCS - Equipe CÏSCO, F-59000 Lille, France.
Unité de catalyse et de chimie du solide de Lille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the field of host-guest chemistry, some of the most widely used hosts are probably cyclodextrins (CDs). As CDs are able to increase the water solubility of numerous drugs by inclusion into their hydrophobic cavity, they have been widespread used to develop numerous pharmaceutical formulations. Nevertheless, CDs are also able to interact with endogenous substances that originate from an organism, tissue or cell. These interactions can be useful for a vast array of topics including cholesterol manipulation, treatment of Alzheimer's disease, control of pathogens, etc. In addition, the use of natural CDs offers the great advantage of avoiding or reducing the use of common petroleum-sourced drugs. In this paper, the general features and applications of CDs have been reviewed as well as their interactions with isolated biomolecules leading to the formation of inclusion or exclusion complexes. Finally, some potential medical applications are highlighted throughout several examples.

Indexed as

cellular interactionscyclodextrinsendogenous substancesextractiongreener active ingredientshost–guest chemistrylipids

Identifiers

PMID28144335
PMCPMC5238526
OpenAlexW2559971549

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.