Evidence map›Paper›PMID 28150111›Full record

ReviewHeart failure reviews2017

SPECT and PET in ischemic heart failure.

George Angelidis, Gregory Giamouzis, Georgios Karagiannis, Javed Butler, Ioannis Tsougos, Varvara Valotassiou, George Giannakoulas, Nikolaos Dimakopoulos, Andrew Xanthopoulos, John Skoularigis and 2 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Heart failure reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Update of the Brazilian Guideline on Nuclear Cardiology - 2020.Arquivos brasileiros de cardiologia · 2020
    Guideline
  2. Myocardial perfusion imaging in advanced coronary artery disease.European journal of clinical investigation · 2025
    Review
  3. Review
  4. Article
  5. Imaging Advances in Heart Failure.Cardiac failure review · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Role of sex hormones in modulating myocardial perfusion and coronary flow reserve.European journal of nuclear medicine and molecular imaging · 2022
    Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Diagnostic imaging in the management of patients with metabolic syndrome.Translational research : the journal of laboratory and clinical medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

George AngelidisDepartment of Nuclear Medicine, Larissa University Hospital, Larissa, Greece.
Gregory GiamouzisDepartment of Cardiology, Larissa University Hospital, P.O. Box 1425, 411 10, Larissa, Greece. ggiamou@emory.edu.
Georgios KaragiannisDepartment of Transplantation and Mechanical Circulatory Support, Harefield Hospital, London, UK.
Javed ButlerDivision of Cardiology, Stony Brook University, Stony Brook, New York, USA.
Ioannis TsougosDepartment of Nuclear Medicine, Larissa University Hospital, Larissa, Greece.
Varvara ValotassiouDepartment of Nuclear Medicine, Larissa University Hospital, Larissa, Greece.
George GiannakoulasDepartment of Cardiology, AHEPA University Hospital, Thessaloniki, Greece.
Nikolaos DimakopoulosDepartment of Nuclear Medicine, NIMTS Hospital, Athens, Greece.
Andrew XanthopoulosDepartment of Cardiology, Larissa University Hospital, P.O. Box 1425, 411 10, Larissa, Greece.
John SkoularigisDepartment of Cardiology, Larissa University Hospital, P.O. Box 1425, 411 10, Larissa, Greece.
Filippos TriposkiadisDepartment of Cardiology, Larissa University Hospital, P.O. Box 1425, 411 10, Larissa, Greece.
Panagiotis GeorgouliasDepartment of Nuclear Medicine, Larissa University Hospital, Larissa, Greece.
University Hospital of Larissa · GRAHEPA University Hospital · GRHarefield Hospital · GBNIMTS Hospital · GRStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure is a common clinical syndrome associated with significant morbidity and mortality worldwide. Ischemic heart disease is the leading cause of heart failure, at least in the industrialized countries. Proper diagnosis of the syndrome and management of patients with heart failure require anatomical and functional information obtained through various imaging modalities. Nuclear cardiology techniques play a main role in the evaluation of heart failure. Myocardial single photon emission computed tomography (SPECT) with thallium-201 or technetium-99 m labelled tracers offer valuable data regarding ventricular function, myocardial perfusion, viability, and intraventricular synchronism. Moreover, positron emission tomography (PET) permits accurate evaluation of myocardial perfusion, metabolism, and viability, providing high-quality images and the ability of quantitative analysis. As these imaging techniques assess different parameters of cardiac structure and function, variations of sensitivity and specificity have been reported among them. In addition, the role of SPECT and PET guided therapy remains controversial. In this comprehensive review, we address these controversies and report the advances in patient's investigation with SPECT and PET in ischemic heart failure. Furthermore, we present the innovations in technology that are expected to strengthen the role of nuclear cardiology modalities in the investigation of heart failure.

Indexed as

Heart FailureMyocardial IschemiaDisease ProgressionGlobal HealthHeartHumansMorbidityPositron-Emission TomographyReproducibility of ResultsSeverity of Illness IndexSurvival RateTomography, Emission-Computed, Single-Photon18-fluoro-deoxyglucoseHeart failureIschemicPETPositron emission tomographyRubidium-82Single photon emission computed tomographySPECTTechnetium-99 mThallium-201Viability

Identifiers

PMID28150111
OpenAlexW2584394745

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.