ArticleCirculation. Cardiovascular imaging2017
Factors Associated With Left Atrial Remodeling in the General Population.
Article in Circulation. Cardiovascular imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 59 citations in OpenAlex.
- Empagliflozin and left atrial function in patients with type 2 diabetes mellitus and coronary artery disease: insight from the EMPA-HEART CardioLink-6 randomized clinical trial.Cardiovascular diabetology · 2024Trial
- Cardiovascular magnetic resonance-derived left atrioventricular coupling index for predicting adverse cardiac outcomes in patients with ischemic cardiomyopathy.International journal of cardiology. Cardiovascular risk and prevention · 2026Article
- Epicardial Adipose Tissue Volume and Left Atrial Remodeling: A J-Shaped Association in Older Adults.Journal of cardiovascular development and disease · 2026Article
- Genetic Determinants of Left Atrial Function Are Associated With Stroke.Journal of the American Heart Association · 2024Article
- Association of Cumulative Systolic Blood Pressure With Left Atrial Function in the Setting of Normal Left Atrial Size: The Atherosclerosis Risk in Communities (ARIC) Study.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2024Article
- Body Fat Distribution and Left Atrial Reverse Remodeling After Catheter Ablation for Atrial Fibrillation.JACC. Advances · 2024Article
- Associations Between Cardiac Function and Brain Health in Diverse Middle-Aged Adults: The Dallas Heart Study-2.JACC. Advances · 2024Article
- Adiposity-associated atrial fibrillation: molecular determinants, mechanisms, and clinical significance.Cardiovascular research · 2023Review
- Association of Number of Live Births With Electrocardiographic and Cardiac Structural Changes.Journal of the American Heart Association · 2022Article
- Association of Whole-Heart Myocardial Mechanics by Transthoracic Echocardiography with Presence of Late Gadolinium Enhancement by CMR in Non-Ischemic Dilated Cardiomyopathy.Journal of clinical medicine · 2022Article
- From Structural to Functional Hypertension Mediated Target Organ Damage-A Long Way to Heart Failure with Preserved Ejection Fraction.Journal of clinical medicine · 2022Review
- Association of Left Atrial Sphericity with Risk of Stroke in Patients with Atrial Fibrillation. Sub-Analysis of the ASSAM Study.Cardiovascular engineering and technology · 2022Observational
- The Added Value of Atrial Strain Assessment in Clinical Practice.Diagnostics (Basel, Switzerland) · 2022Review
- Left atrial reverse remodeling improves risk stratification in patients with heart failure with recovered ejection fraction.Scientific reports · 2022Article
- Left atrial-left ventricular angle, a new measure of left atrial and left ventricular remodeling.The international journal of cardiovascular imaging · 2022Article
- Left atrial structural and mechanical remodelling in heart failure with reduced ejection fraction.ESC heart failure · 2021Article
- Atrial structure and function in middle-aged, physically-active males and females: A cardiac magnetic resonance study.Clinical cardiology · 2021Article
- Left Atrioventricular Coupling Index as a Prognostic Marker of Cardiovascular Events: The MESA Study.Hypertension (Dallas, Tex. : 1979) · 2021Article
- Association of Longitudinal Changes in NT-proBNP With Changes in Left Atrial Volume and Function: MESA.American journal of hypertension · 2021Article
- Contemporary narrative review on left atrial strain mechanics in echocardiography: cardiomyopathy, valvular heart disease and beyond.Cardiovascular diagnosis and therapy · 2021Review
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Authors and funding
10 authors at 3 institutions in 3 countries.
Funding
Abstract
backgroundAlthough contributors to remodeling of the left ventricle (LV) have been well studied in general population cohorts, few data are available describing factors influencing changes in left atrial (LA) structure. METHODS AND
resultsMaximum LA volume was determined by cardiac magnetic resonance imaging among 748 participants in the Dallas Heart Study at 2 visits a mean of 8 years apart. Associations of changes in LA volume (ΔLAV) with traditional risk factors, biomarkers, LV geometry, and remodeling by cardiac magnetic resonance imaging and detailed measurements of global and regional adiposity (by magnetic resonance imaging and dual-energy x ray absorptiometry) were assessed using multivariable linear regression. Greater ΔLAV was independently associated with black and Hispanic race/ethnicity, change in systolic blood pressure, LV mass and ΔLV mass, N-terminal probrain natriuretic peptide and change in N-terminal probrain natriuretic peptide, and body mass index (P<0.05 for each). In subanalyses, the associations of ΔLAV with LV mass parameters were driven by associations with baseline and ΔLV end diastolic volume (P<0.0001 for each) and not wall thickness (P=0.21). Associations of ΔLAV with body mass index were explained exclusively by associations with visceral fat mass (P=0.002), with no association seen between ΔLAV and subcutaneous abdominal fat (P=0.47) or lower body fat (P=0.30).
conclusionsLeft atrial dilatation in the population is more common in black and Hispanic than in white individuals and is associated with parallel changes in the LV. LA dilatation may be mediated by blood pressure control and the development of visceral adiposity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.