ArticleJournal of Alzheimer's disease : JAD2017
Financial and Health Literacy Predict Incident Alzheimer's Disease Dementia and Pathology.
Article in Journal of Alzheimer's disease : JAD, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- APOE ε4 and Decline in Health and Financial Literacy in Advanced Age.Journal of the American Geriatrics Society · 2026Article
- Health and Financial Literacy and the Acquisition of COVID-19 Knowledge in Older Adults.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2025Article
- Assessing the Role of the Generative Pretrained Transformer (GPT) in Alzheimer's Disease Management: Comparative Study of Neurologist- and Artificial Intelligence-Generated Responses.Journal of medical Internet research · 2024Article
- The Relationship of MRI-Derived Alzheimer's and Cerebrovascular-Related Signatures With Level of and Change in Health and Financial Literacy.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2023Article
- Association of Denture Use and Chewing Ability with Cognitive Function Analysed Using Panel Data from Korea Longitudinal Study of Aging (2006-2018).Healthcare (Basel, Switzerland) · 2023Article
- Limbic-predominant age-related TDP43 encephalopathy (LATE) neuropathological change in neurodegenerative diseases.Nature reviews. Neurology · 2023Review
- Well-Being and Aging-Related Decline in Financial and Health Literacy in Advanced Age.The journals of gerontology. Series B, Psychological sciences and social sciences · 2023Article
- Understanding the role of financial health literacy in midlife and old age: A scoping review.Health & social care in the community · 2022Article
- The Relationship between Subjective Cognitive Decline and Health Literacy in Healthy Community-Dwelling Older Adults.Healthcare (Basel, Switzerland) · 2020Article
- What does (low) education mean in terms of dementia risk? A systematic review and meta-analysis highlighting inconsistency in measuring and operationalising education.SSM - population health · 2020Review
- Associations of health and financial literacy with mortality in advanced age.Aging clinical and experimental research · 2020Observational
- Decline in Literacy and Incident AD Dementia Among Community-Dwelling Older Persons.Journal of aging and health · 2018Article
- Correlates of healthcare and financial decision making among older adults without dementia.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2018Article
- Religious Orders Study and Rush Memory and Aging Project.Journal of Alzheimer's disease : JAD · 2018Review
- Association of TDP-43 Pathology With Domain-specific Literacy in Older Persons.Alzheimer disease and associated disordersArticle
- Article
- How Is Literacy Being Defined and Measured in Dementia Research? A Scoping Review.Gerontology & geriatric medicineArticle
- Expanding the Toolkit for Studies of Aging.The journal of prevention of Alzheimer's diseaseArticle
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
backgroundDomain specific literacy is a multidimensional construct that requires multiple resources including cognitive and non-cognitive factors.
objectiveWe test the hypothesis that domain specific literacy is associated with Alzheimer's disease (AD) dementia and AD pathology after controlling for cognition.
methodsParticipants were community-based older persons who completed a baseline literacy assessment, underwent annual clinical evaluations for up to 8 years, and agreed to organ donation after death. Financial and health literacy was measured using 32 questions and cognition was measured using 19 tests. Annual diagnosis of AD dementia followed standard criteria. AD pathology was examined postmortem by quantifying plaques and tangles. Cox models examined the association of literacy with incident AD dementia. Performance of model prediction for incident AD dementia was assessed using indices for integrated discrimination improvement and continuous net reclassification improvement. Linear regression models examined the independent association of literacy with AD pathology in autopsied participants.
resultsAll 805 participants were free of dementia at baseline and 102 (12.7%) developed AD dementia during the follow-up. Lower literacy was associated with higher risk for incident AD dementia (p < 0.001), and the association persisted after controlling for cognition (hazard ratio = 1.50, p = 0.004). The model including the literacy measure had better predictive performance than the one with demographics and cognition only. Lower literacy also was associated with higher burden of AD pathology after controlling for cognition (β= 0.07, p = 0.035).
conclusionLiteracy predicts incident AD dementia and AD pathology in community-dwelling older persons, and the association is independent of traditional measures of cognition.
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