Evidence map›Paper›PMID 28166118›Full record

Trial reportMedicine and science in sports and exercise2017

All-Extremity Exercise Training Improves Arterial Stiffness in Older Adults.

Han-Kyul Kim, Chueh-Lung Hwang, Jeung-Ki Yoo, Moon-Hyon Hwang, Eileen M Handberg, John W Petersen, Wilmer W Nichols, Sofia Sofianos, Demetra D Christou

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Medicine and science in sports and exercise, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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  10. Meta-Analysis of the Effect of Different Exercise Mode on Carotid Atherosclerosis.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Han-Kyul Kim1Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL; 2Division of Health and Exercise Science, Incheon National University, Incheon, KOREA; and 3Division of Cardiovascular Medicine, University of Florida, Gainesville, FL.
Chueh-Lung Hwang
Jeung-Ki Yoo
Moon-Hyon Hwang
Eileen M Handberg
John W Petersen
Wilmer W Nichols
Sofia Sofianos
Demetra D Christou

Funding

Endothelial Dysfunction in Older Adults with Type 2 Diabetes: Effect of ExerciseR21AG050203 · NIA · UNIVERSITY OF FLORIDA · PI CHRISTOU, DEMETRA · 2015 to 2015
$225k
NIA NIH HHS R21 AG050203
6 · The paper itself

Abstract

Large elastic arteries stiffen with age, which predisposes older adults to increased risk for cardiovascular disease. Aerobic exercise training is known to reduce the risk for cardiovascular disease, but the optimal exercise prescription for attenuating large elastic arterial stiffening in older adults is not known. PURPOSE: The purpose of this randomized controlled trial was to compare the effect of all-extremity high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on aortic pulse wave velocity (PWV) and carotid artery compliance in older adults.

methodsForty-nine sedentary older adults (age = 64 ± 1 yr), free of overt major clinical disease, were randomized to HIIT (n = 17), MICT (n = 18), or nonexercise controls (CONT; n = 14). HIIT (4 × 4 min at 90% HRpeak interspersed with 3 × 3 min active recovery at 70% HRpeak) and isocaloric MICT (70% HRpeak) were performed on an all-extremity non-weight-bearing ergometer, 4 d·wk for 8 wk under supervision. Aortic (carotid to femoral PWV [cfPWV]) and common carotid artery compliance were assessed at pre- and postintervention.

resultscfPWV improved by 0.5 m·s in MICT (P = 0.04) but did not significantly change in HIIT and CONT (P > 0.05). Carotid artery compliance improved by 0.03 mm·mm Hg in MICT (P = 0.001), but it remained unchanged in HIIT and CONT (P > 0.05). Improvements in arterial stiffness in response to MICT were not confounded by changes in aortic or brachial blood pressure, HR, body weight, total and abdominal adiposity, blood lipids, or aerobic fitness.

conclusionAll-extremity MICT, but not HIIT, improved central arterial stiffness in previously sedentary older adults free of major clinical disease. Our findings have important implications for aerobic exercise prescription in older adults.

Indexed as

AgedAnthropometryAortaBlood PressureCarotid ArteriesFemaleHeart RateHigh-Intensity Interval TrainingHumansLipidsLower ExtremityMaleMiddle AgedPulse Wave AnalysisUpper ExtremityVascular StiffnessLipids

Identifiers

PMID28166118
PMCPMC5474160

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.