Evidence map›Paper›PMID 28167097›Full record

ReviewNeuroscience and biobehavioral reviews2017

The BTBR mouse model of idiopathic autism - Current view on mechanisms.

K Z Meyza, D C Blanchard

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed, 4 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

106 citing papers in PubMed, 4 syntheses or guidelines pooled it, 178 citations in OpenAlex.

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46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

K Z MeyzaLaboratory of Emotions' Neurobiology, Nencki Institute of Experimental Biology, 3 Pasteur Street, Warsaw, 02-093, Poland. Electronic address: k.meyza@nencki.gov.pl.
D C BlanchardDepartment of Psychology, University of Hawaii at Manoa,1993 East-West Road, Honolulu, HI 96822, USA.
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego · PLUniversity of Hawaiʻi at Mānoa · US

Funding

The Genetic Control of Social Behavior in the MouseR01MH081845 · NIMH · UNIVERSITY OF HAWAII AT MANOA · PI BLANCHARD, DIXIE CAROLINE · 2009 to 2012
$1.6M
NIMH NIH HHS R01 MH081845
6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is the most commonly diagnosed neurodevelopmental disorder, with current estimates of more than 1% of affected children across nations. The patients form a highly heterogeneous group with only the behavioral phenotype in common. The genetic heterogeneity is reflected in a plethora of animal models representing multiple mutations found in families of affected children. Despite many years of scientific effort, for the majority of cases the genetic cause remains elusive. It is therefore crucial to include well-validated models of idiopathic autism in studies searching for potential therapeutic agents. One of these models is the BTBR T

Indexed as

Autistic DisorderAnimalsAutism Spectrum DisorderDisease Models, AnimalHumansMiceMice, Inbred StrainsSocial BehaviorBTBRMolecular mechanismsNeuroanatomyPharmacological manipulationsRepetitive behaviorSocial behavior

Identifiers

PMID28167097
PMCPMC5403558
OpenAlexW2585844730

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.