Evidence mapPaperPMID 28167447Full record

ArticleEnvironmental research2017

Associations between ambient wood smoke and other particulate pollutants and biomarkers of systemic inflammation, coagulation and thrombosis in cardiac patients.

Daniel P Croft, Scott J Cameron, Craig N Morrell, Charles J Lowenstein, Frederick Ling, Wojciech Zareba, Philip K Hopke, Mark J Utell, Sally W Thurston, Kelly Thevenet-Morrison and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Environmental research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Effects of Particulate Matter on Inflammation and Thrombosis: Past Evidence for Future Prevention.International journal of environmental research and public health · 2022
    Review
  13. Article
  14. Cold Climate Impact on Air-Pollution-Related Health Outcomes: A Scoping Review.International journal of environmental research and public health · 2022
    Article
  15. Review
  16. Review
  17. Sub-Clinical Effects of Outdoor Smoke in Affected Communities.International journal of environmental research and public health · 2021
    Article
  18. Review
  19. Observational
  20. Cardiovascular adaptations to particle inhalation exposure: molecular mechanisms of the toxicology.American journal of physiology. Heart and circulatory physiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Daniel P CroftDivision of Pulmonary and Critical Care, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: Daniel_Croft@URMC.Rochester.edu.
Scott J CameronDivision of Cardiology, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: Scott_Cameron@URMC.Rochester.edu.
Craig N MorrellDivision of Cardiology, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: Craig_Morrell@URMC.Rochester.edu.
Charles J LowensteinDivision of Cardiology, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: charles_lowenstein@urmc.rochester.edu.
Frederick LingDivision of Cardiology, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: Fred_Ling@URMC.Rochester.edu.
Wojciech ZarebaDivision of Cardiology, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: Wojciech_Zareba@URMC.Rochester.edu.
Philip K HopkeInstitute for a Sustainable Environment, and Center for Air Resources Engineering and Science, Clarkson University, Box 5708, Potsdam, NY 13699-5708, USA; Department of Public Health Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: phopke@clarkson.edu.
Mark J UtellDivision of Pulmonary and Critical Care, Department of Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA; Department of Environmental Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: Mark_Utell@URMC.Rochester.edu.
Sally W ThurstonDepartment of Biostatistics and Computational Biology, University of Rochester, University of Rochester Medical Center, Saunders Research Building, 265 Crittenden Blvd., Box 630, Rochester, NY 14642, USA. Electronic address: Sally_Thurston@URMC.Rochester.edu.
Kelly Thevenet-MorrisonDepartment of Public Health Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: Kelly_Thevenet-morrison@URMC.Rochester.edu.
Kristin A EvansDepartment of Public Health Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: kristin.evans@truvenhealth.com.
David ChalupaDepartment of Public Health Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: David_Chalupa@URMC.Rochester.edu.
David Q RichDepartment of Public Health Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA; Department of Environmental Medicine, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY, USA. Electronic address: David_Rich@URMC.Rochester.edu.
University of Rochester Medical Center · USClarkson University · US

Funding

VISUAL INDICES OF NEUROTOXICITYP30ES001247 · UNIVERSITY OF ROCHESTER · 1985 to 2025
$10.5M
Multidisciplinary Training in Pulmonary ResearchT32HL066988 · UNIVERSITY OF ROCHESTER · 2001 to 2005
$2.0M
NHLBI NIH HHS K08 HL128856NHLBI NIH HHS T32 HL066988NIEHS NIH HHS P30 ES001247
6 · The paper itself

Abstract

backgroundIncreased particulate air pollution has been associated with both an increased risk of myocardial infarction (MI) and adverse changes in cardiac biomarkers. Up to 30% of ambient wintertime fine particles (PM

methodsWe measured blood concentrations of C-reactive protein (CRP), D-dimer, fibrinogen, P-selectin, platelet factor 4 (PF-4), von Willebrand factor (vWF), and myeloperoxidase (MPO) of 135 patients undergoing cardiac catheterization during the winters of 2011-2013. We coupled these data with hourly ambient concentrations of Delta-C, black carbon (BC; marker of traffic pollution), and ultrafine (10-100nm; UFP), accumulation mode (100-500nm; AMP), and fine particles (<2.5µm; PM

resultsEach 0.13µg/m

conclusionsIn a population of cardiac patients, we noted adverse changes in fibrinogen associated with increased concentrations of a marker of wood smoke. Increases in PM

Indexed as

AdultAgedAged, 80 and overBiomarkersBlood CoagulationC-Reactive ProteinEnvironmental ExposureFemaleFibrinogenHeart DiseasesHumansInflammationMaleMiddle AgedNew YorkParticulate MatterBiomarkersC-Reactive ProteinFibrinogenParticulate MatterPeroxidaseP-SelectinSmokevon Willebrand FactorAir pollutionDelta-CFibrinogenInflammationWood smoke

Identifiers

PMID28167447
PMCPMC5375102
OpenAlexW2584838673

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.