Evidence map›Paper›PMID 28168441›Full record

ArticleNeurotoxicity research2017

Late Effect of Developmental Exposure to 3,3'-Iminodipropionitrile on Neurogenesis in the Hippocampal Dentate Gyrus of Mice.

Yasuko Hasegawa-Baba, Takeshi Tanaka, Yousuke Watanabe, Liyun Wang, Megu Itahashi, Toshinori Yoshida, Makoto Shibutani

Abstract read
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In one paragraph

Article in Neurotoxicity research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yasuko Hasegawa-BabaLaboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Takeshi TanakaLaboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Yousuke WatanabeLaboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Liyun WangLaboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Megu ItahashiLaboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Toshinori YoshidaLaboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan.
Makoto ShibutaniLaboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo, 183-8509, Japan. mshibuta@cc.tuat.ac.jp.ORCID http://orcid.org/0000-0003-3417-9697
Tokyo University of Agriculture and Technology · JPGifu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The effects of developmental exposure to 3,3'-iminodipropionitrile (IDPN), a neurotoxicant that causes proximal axonopathy, on mouse hippocampal neurogenesis was examined. Pregnant mice were exposed to IDPN at 0, 600, or 1200 ppm in their drinking water from gestational day 6 to postnatal day (PND) 21. On PND 21, male offspring showed increased postmitotic neuron-specific NeuN-immunoreactive

Indexed as

Dentate GyrusAge FactorsAnimalsAnimals, NewbornApoptosisBody WeightCell ProliferationCytoskeletal ProteinsDoublecortin ProteinEmbryo, MammalianFatty Acid-Binding Protein 7Gene Expression Regulation, DevelopmentalMiceMice, Inbred ICRNecrosisNerve Tissue Proteins3,3'-iminodipropionitrileactivity regulated cytoskeletal-associated proteinCytoskeletal ProteinsDcx protein, mouseDoublecortin ProteinEomes protein, mouseFabp7 protein, mouseFatty Acid-Binding Protein 7Nerve Tissue ProteinsNitrilesOncogene Proteins v-fosProliferating Cell Nuclear AntigenT-Box Domain Proteins3,3′-Iminodipropionitrile (IDPN)Hippocampal dentate gyrusLate effectMouseNeurogenesis

Identifiers

PMID28168441
OpenAlexW2586375076

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.