ArticlePloS one2017
Association between HbA1c and carotid atherosclerosis among elderly Koreans with normal fasting glucose.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 19 citations in OpenAlex.
- Development and validation of a risk predictive nomogram for carotid intima-media thickening in patients with type 2 diabetes.Acta diabetologica · 2026Article
- Association of carotid atherosclerosis markers with all-cause and cardiovascular disease-specific mortality in persons with type 2 diabetes: a causal mediation analysis with glucose variation.Acta diabetologica · 2024Article
- The Relationship Between the Serum NLRP3 and Adiponectin Levels and Coronary Lesions in Patients with Unstable Angina with Type 2 Diabetes.Clinical interventions in aging · 2024Article
- Factors affecting Hemoglobin A1c in the longitudinal study of the Iranian population using mixed quantile regression.Scientific reports · 2023Article
- The Relationship between Selected Inflammation and Oxidative Stress Biomarkers and Carotid Intima-Media Thickness (IMT) Value in Youth with Type 1 Diabetes Co-Existing with Early Microvascular Complications.Journal of clinical medicine · 2022Article
- Cohort profile: Korean Urban Rural Elderly (KURE) study, a prospective cohort on ageing and health in Korea.BMJ open · 2019Article
- Influence of glycosylated hemoglobin on the choroidal thickness.International ophthalmology · 2018Article
- Factors associated with carotid Intima media thickness and carotid plaque score in community-dwelling and non-diabetic individuals.BMC cardiovascular disorders · 2018Article
- Hemoglobin ACardiovascular diabetology · 2017Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimWe examined whether glycated haemoglobin (HbA1c) is associated to carotid atherosclerosis in an elderly Korean population with normal fasting glucose.
methodsUsing data from the Korean Urban Rural Elderly study, we conducted a cross-sectional analysis of 1,133 participants (335 men and 798 women) with a mean age of 71.8 years. All participants had fasting blood glucose less than 100mg/dL (5.6 mmol/L) and HbA1c level below 6.5% (48 mmol/mol). They were also free from a history of cardiovascular disease, known type 2 diabetes mellitus or use of anti-diabetes medications. Carotid atherosclerosis was assessed by intima-media thickness (IMT) using ultrasonography. The association between HbA1c and carotid IMT was investigated using multivariable linear regression analysis.
resultsHbA1c levels were independently and positively associated with carotid IMT (β = 0.020, p = 0.045) after adjusting for sex, age, body mass index, systolic blood pressure, diastolic blood pressure, triglyceride, LDL cholesterol, smoking and alcohol intake. However, fasting insulin and glucose levels were not associated with carotid IMT.
conclusionHbA1c levels were positively associated with carotid atherosclerosis, as assessed by carotid IMT, in an elderly population with normoglycemia. Our study suggested that higher HbA1c level is an effective and informative marker of carotid atherosclerosis in an elderly population.
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