Evidence mapPaperPMID 28255159Full record

ArticleScientific reports2017

High intensity aerobic exercise training improves chronic intermittent hypoxia-induced insulin resistance without basal autophagy modulation.

Marion Pauly, Allan Assense, Aurélie Rondon, Amandine Thomas, Hervé Dubouchaud, Damien Freyssenet, Henri Benoit, Josiane Castells, Patrice Flore

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Exercise and Organ Cross Talk.Advances in experimental medicine and biology · 2020
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Marion PaulyGrenoble Alpes University, HP2 laboratory, Grenoble, F-38042, France.
Allan AssenseGrenoble Alpes University, HP2 laboratory, Grenoble, F-38042, France.
Aurélie RondonGrenoble Alpes University, HP2 laboratory, Grenoble, F-38042, France.
Amandine ThomasGrenoble Alpes University, HP2 laboratory, Grenoble, F-38042, France.
Hervé DubouchaudINSERM, U1055, LBFA, Grenoble Alpes University, Grenoble, France.
Damien FreyssenetUniversité Lyon, Université Jean Monnet Saint Etienne, Laboratoire Interuniversitaire de Biologie de la Motricité, EA7424, F-42023, Saint Etienne, France.
Henri BenoitGrenoble Alpes University, HP2 laboratory, Grenoble, F-38042, France.
Josiane CastellsUniversité Lyon, Université Jean Monnet Saint Etienne, Laboratoire Interuniversitaire de Biologie de la Motricité, EA7424, F-42023, Saint Etienne, France.
Patrice FloreGrenoble Alpes University, HP2 laboratory, Grenoble, F-38042, France.
Inserm · FRUniversité Grenoble Alpes · FRLaboratoire Interuniversitaire de Biologie de la Motricité · FRUniversité Claude Bernard Lyon 1 · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic intermittent hypoxia (IH) associated with obstructive sleep apnea (OSA) is a major risk factor for cardiovascular and metabolic diseases (insulin resistance: IR). Autophagy is involved in the pathophysiology of IR and high intensity training (HIT) has recently emerged as a potential therapy. We aimed to confirm IH-induced IR in a tissue-dependent way and to explore the preventive effect of HIT on IR-induced by IH. Thirty Swiss 129 male mice were randomly assigned to Normoxia (N), Intermittent Hypoxia (IH: 21-5% FiO

Indexed as

AutophagyInsulin ResistancePhysical Conditioning, AnimalAdipose TissueAnimalsBiomarkersBody WeightEatingHematocritHypoxiaInsulinLiverMaleMiceMuscle, SkeletalSignal TransductionBiomarkersInsulin

Identifiers

PMID28255159
PMCPMC5334652
OpenAlexW2593078907

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.