SynthesisItalian journal of pediatrics2017
The link between obesity and migraine in childhood: a systematic review.
Synthesis in Italian journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- The 200 most influential publications in migraine research: a bibliometric mapping of the intellectual landscape.Frontiers in neurology · 2025Pooled it
- Association between weight status and migraine in the paediatric population: a systematic review and meta-analysis.Frontiers in neurology · 2023Pooled it
- Comparison of the efficacy of two different desmopressin formulations in pediatric patients with nocturnal enuresis: a retrospective observational study.Central European journal of urology · 2026Article
- Is it possible to predict the response to therapy in enuretic children? The PiFe score.Central European journal of urology · 2025Article
- Probiotic and high-fat diet: effects on pain assessment, body composition, and cytokines in male and female adolescent and adult rats.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Article
- Not Only Metabolic Complications of Childhood Obesity.Nutrients · 2024Review
- A Descriptive Review of Medication-Overuse Headache: From Pathophysiology to the Comorbidities.Brain sciences · 2023Review
- Comorbidities of Rural Children and Adolescents with Migraine and without Migraine.Children (Basel, Switzerland) · 2023Article
- Clinical review: Guide to pharmacological management in pediatric obesity medicine.Obesity pillars · 2023Review
- Cardiovascular Risk Factors and Family History of Major Thrombotic Events in Children with Migraine: A 12-Year Retrospective Single-Centre Study.Journal of clinical medicine · 2023Article
- Article
- Truths and Myths in Pediatric Migraine and Nutrition.Nutrients · 2021Review
- Circulating inflammatory biomarkers in adolescents: evidence of interactions between chronic pain and obesity.Pain reports · 2021Article
- Metabolic Aspects of Migraine: Association With Obesity and Diabetes Mellitus.Frontiers in neurology · 2021Review
- Observational
- Impact of Puberty in Girls on Prevalence of Primary Headache Disorder Among Female Schoolchildren in Kuwait.Frontiers in neurology · 2020Article
- Anxiety, Depression, and Body Weight in Children and Adolescents With Migraine.Frontiers in psychology · 2020Article
- Predictors of Short-Term Prognosis While in Pediatric Headache Care: An Observational Study.Headache · 2019Observational
- Advances in pediatrics in 2017: current practices and challenges in allergy, endocrinology, gastroenterology, genetics, immunology, infectious diseases, neonatology, nephrology, neurology, pulmonology from the perspective of Italian Journal of Pediatrics.Italian journal of pediatrics · 2018Review
- Non-Rapid Eye Movement Sleep Parasomnias and Migraine: A Role of Orexinergic Projections.Frontiers in neurology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obesity and headache are two highly prevalent diseases both in adults and children and they are associated with a strong personal and social impact. Many studies suggest that obesity is comorbid with headache in general, and migraine in particular and obesity seems to be a risk factor for migraine progression and for migraine frequency both in adults and in children. Research shows that there are multiple areas of overlap between migraine pathophysiology and the central and peripheral pathways regulating feeding: inflammatory mediators such as the calcitonin gene-related protein (CGRP), neurotransmitters such as serotonin, peptides such as orexin and adipocytokines such as adiponectin (ADP) and leptin could explain the common pathogenesis. In this paper we discussed the association between obesity and migraine through the analysis of the most recent studies in children and we reviewed data from literature in order to assess the association between obesity and headache and to clarify the possible common pathogenic mechanisms.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.