ArticleScientific reports2017
Accuracy and safety verification of ovarian reserve assessment technique for ovarian tissue transplantation using optical coherence tomography in mice ovary.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 26 citations in OpenAlex.
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- Novel imaging and biophysical approaches to study tissue hydraulics in mammalian folliculogenesis.Biophysical reviews · 2024Review
- Three-dimensional imaging and quantification of mouse ovarian follicles via optical coherence tomography.Biomedical optics express · 2023Article
- Three-dimensional imaging and quantification of mouse ovarian follicles via optical coherence tomography.bioRxiv : the preprint server for biology · 2023Article
- Quantification and visualization of metastatic lung tumors in mice.Toxicological research · 2022Article
- In Vitro Activation Early Follicles: From the Basic Science to the Clinical Perspectives.International journal of molecular sciences · 2021Review
- Endometrium imaging using real-time rotational optical coherence tomography imaging system: A pilot, prospective and ex-vivo study.Medicine · 2019Observational
- Current state and future possibilities of ovarian tissue transplantation.Reproductive medicine and biology · 2019Review
- Endometrial Vascularization Characterized by Optical Coherence Tomography and Immunohistochemistry in Women Undergoing In Vitro Fertilization-Embryo Transfer Treatment.Medicina (Kaunas, Lithuania) · 2019Article
- Evaluation of segmentation algorithms for optical coherence tomography images of ovarian tissue.Journal of medical imaging (Bellingham, Wash.) · 2019Article
- Fertility preservation for adolescent and young adult cancer patients in Japan.Obstetrics & gynecology science · 2018Review
- Preliminary human application of optical coherence tomography for quantification and localization of primordial follicles aimed at effective ovarian tissue transplantation.Journal of assisted reproduction and genetics · 2018Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Except for histological study, there are currently no suitable techniques available for the detection and identification of primordial follicles in ovary of primary ovarian insufficiency patients who have undetectable AMH levels. Also, the ability to locate and quantify follicles on ovarian cortex strips, without fixation, is valuable for patients who could undergo subsequent successful ovarian tissue transplantation. Although optical coherence tomography (OCT) is a well-established high resolution imaging technique without fixation commonly applied in biomedicine, few reports are available on ovarian tissue imaging. In present study, we established standard OCT follicle images at each developmental stage, including the primordial follicle, and demonstrated the efficacy of OCT to estimate IVF outcome in transplanted mice ovary like ovarian reserve tests. Unfortunately, the current commercial OCT could not be used to accurate follicle count the number of follicles for whole ovary, because the maximum depth of examination was 100 μm. And we demonstrated the safety of OCT examination, it did not affect IVF outcome and birth defect rate, and reproductive ability. Although there is room for improvement, these findings will be first step to bring OCT examination a step closer to clinical application for measuring true ovarian reserve and localizing follicles.
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