Evidence map›Paper›PMID 28275384›Full record

ReviewElectrolyte & blood pressure : E & BP2016

Genetic Variations of Tyrosine Hydroxylase in the Pathogenesis of Hypertension.

Yu Ho Lee, Yang Gyun Kim, Ju-Young Moon, Jin Sug Kim, Kyung-Hwan Jeong, Tae Won Lee, Chun-Gyoo Ihm, Sang Ho Lee

Open access · diamondAbstract readReview
In one paragraph

Review in Electrolyte & blood pressure : E & BP, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Forty years of the adrenal chromaffin cell through ISCCB meetings around the world.Pflugers Archiv : European journal of physiology · 2023
    Review
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yu Ho LeeDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Yang Gyun KimDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Ju-Young MoonDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Jin Sug KimDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Kyung-Hwan JeongDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Tae Won LeeDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Chun-Gyoo IhmDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Sang Ho LeeDivision of Nephrology, Department of Internal Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

One of the major pathophysiological features of primary hypertension is an inappropriate activation of the sympathetic nervous system, which is mediated by excessive synthesis and secretion of catecholamine into the blood. Tyrosine hydroxylase (TH), a rate-limiting enzyme in the synthesis of catecholamine, has been highlighted because genetic variations of

Indexed as

HypertensionSingle nucleotide polymorphismTyrosine hydroxylase

Identifiers

PMID28275384
PMCPMC5337429
OpenAlexW2594799214

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.