ArticleG3 (Bethesda, Md.)2017
The Interaction of Genetic Background and Mutational Effects in Regulation of Mouse Craniofacial Shape.
Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Gene-environment interactions modulate the phenotype severity in mouse models of congenital craniofacial syndromes.The Journal of clinical investigation · 2025Article
- New CRISPR/Cas9-based Fgfr2Journal of molecular medicine (Berlin, Germany) · 2024Article
- Foraging-induced craniofacial plasticity is associated with an early, robust and dynamic transcriptional response.Proceedings. Biological sciences · 2024Article
- Craniosynostosis, inner ear, and renal anomalies in a child with complete loss ofJournal of medical genetics · 2023Article
- Article
- Spatiotemporal Expression Patterns of Critical Genes Involved in FGF Signaling During Morphogenesis and Odontogenesis of Deciduous Molars in Miniature Pigs.International journal of medical sciences · 2022Article
- Article
- The Mafb cleft-associated variant H131Q is not required for palatogenesis in the mouse.Developmental dynamics : an official publication of the American Association of Anatomists · 2021Article
- Variation in phenotypes from a Bmp-Gata3 genetic pathway is modulated by Shh signaling.PLoS genetics · 2021Article
- ADAMTS9 and ADAMTS20 are differentially affected by loss of B3GLCT in mouse model of Peters plus syndrome.Human molecular genetics · 2019Article
- Selective breeding modifies mef2ca mutant incomplete penetrance by tuning the opposing Notch pathway.PLoS genetics · 2019Article
- Gpr63 is a modifier of microcephaly in Ttc21b mouse mutants.PLoS genetics · 2019Article
- Downregulation of FGF Signaling byJBMR plus · 2019Article
- The developmental-genetics of canalization.Seminars in cell & developmental biology · 2019Review
- Feedback regulation of RTK signaling in development.Developmental biology · 2019Review
- Mouse Skull Mean Shape and Shape Robustness Rely on Different Genetic Architectures and Different Loci.Frontiers in genetics · 2019Article
- Developmental processes regulate craniofacial variation in disease and evolution.Genesis (New York, N.Y. : 2000) · 2019Review
- Genetic backgrounds and hidden trait complexity in natural populations.Current opinion in genetics & development · 2017Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Inbred genetic background significantly influences the expression of phenotypes associated with known genetic perturbations and can underlie variation in disease severity between individuals with the same mutation. However, the effect of epistatic interactions on the development of complex traits, such as craniofacial morphology, is poorly understood. Here, we investigated the effect of three inbred backgrounds (129X1/SvJ, C57BL/6J, and FVB/NJ) on the expression of craniofacial dysmorphology in mice (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.