Evidence map›Paper›PMID 28280737›Full record

ArticleBioMed research international2017

Bioinformatics Study of Structural Patterns in Plant MicroRNA Precursors.

J Miskiewicz, K Tomczyk, A Mickiewicz, J Sarzynska, M Szachniuk

Abstract read
In one paragraph

Article in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. RNAloops: a database of RNA multiloops.Bioinformatics (Oxford, England) · 2022
    Article
  10. How bioinformatics resources work with G4 RNAs.Briefings in bioinformatics · 2021
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. [Effect of microRNA-29b on proliferation and migration of breast cancer cells and its molecular mechanism].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

J MiskiewiczInstitute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan, Poland.ORCID 0000-0002-4563-7481
K TomczykInstitute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan, Poland.
A MickiewiczInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
J SarzynskaInstitute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
M SzachniukInstitute of Computing Science and European Centre for Bioinformatics and Genomics, Poznan University of Technology, Poznan, Poland; Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.ORCID 0000-0002-8724-7908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

According to the RNA world theory, RNAs which stored genetic information and catalyzed chemical reactions had their contribution in the formation of current living organisms. In recent years, researchers studied this molecule diversity, i.a. focusing on small non-coding regulatory RNAs. Among them, of particular interest is evolutionarily ancient, 19-24 nt molecule of microRNA (miRNA). It has been already recognized as a regulator of gene expression in eukaryotes. In plants, miRNA plays a key role in the response to stress conditions and it participates in the process of growth and development. MicroRNAs originate from primary transcripts (pri-miRNA) encoded in the nuclear genome. They are processed from single-stranded stem-loop RNA precursors containing hairpin structures. While the mechanism of mature miRNA production in animals is better understood, its biogenesis in plants remains less clear. Herein, we present the results of bioinformatics analysis aimed at discovering how plant microRNAs are recognized within their precursors (pre-miRNAs). The study has been focused on sequential and structural motif identification in the neighbourhood of microRNA.

Indexed as

Base SequenceComputational BiologyMicroRNAsNucleic Acid ConformationNucleotidesPlantsRNA, PlantRNA PrecursorsMicroRNAsNucleotidesRNA, PlantRNA Precursors

Identifiers

PMID28280737
PMCPMC5322449

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.