Evidence mapPaperPMID 28283467Full record

ArticleCancer prevention research (Philadelphia, Pa.)2017

Responsiveness of

Sahar J Alothman, Weisheng Wang, David S Goerlitz, Md Islam, Xiaogang Zhong, Archana Kishore, Redha I Azhar, Bhaskar V Kallakury, Priscilla A Furth

Open access · greenAbstract read
In one paragraph

Article in Cancer prevention research (Philadelphia, Pa.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. BRCA1 Antibodies Matter.International journal of biological sciences · 2021
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sahar J AlothmanGraduate School of Arts and Science, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Weisheng WangDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
David S GoerlitzDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Md IslamDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Xiaogang ZhongDepartment of Biostatistics, Bioinformatics & Biomathematics, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Archana KishoreDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Redha I AzharDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Bhaskar V KallakuryDepartment of Pathology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC.
Priscilla A FurthDepartment of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC. paf3@georgetown.edu.
Georgetown University · USGeorgetown University Medical Center · US

Funding

Tissue Culture and Biobanking Shared ResourceP30CA051008 · GEORGETOWN UNIVERSITY · 1990 to 2025
$20.3M
Progression and regression of mammary preneoplasiaR01CA112176 · GEORGETOWN UNIVERSITY · 2005 to 2005
$286k
NCI NIH HHS P30 CA051008NCI NIH HHS R01 CA112176
6 · The paper itself

Abstract

An intervention study initiated at age 4 months compared the impact of tamoxifen (25 mg), raloxifene (22.5 mg), and letrozole (2.5 mg) administered by 60-day release subcutaneous pellet on mammary preneoplasia prevalence at age 6 months in conditional genetically engineered mouse models with different Breast cancer 1 (

Indexed as

AnimalsAromatase InhibitorsBRCA1 ProteinFemaleLetrozoleMammary Neoplasms, ExperimentalMiceMice, Inbred C57BLNitrilesPrecancerous ConditionsRaloxifene HydrochlorideSelective Estrogen Receptor ModulatorsTamoxifenTriazolesTumor Suppressor Protein p53Tumor Suppressor ProteinsAromatase InhibitorsBRCA1 ProteinBrca1 protein, mouseLetrozoleNitrilesRaloxifene HydrochlorideSelective Estrogen Receptor ModulatorsTamoxifenTriazolesTumor Suppressor Protein p53Tumor Suppressor Proteins

Identifiers

PMID28283467
PMCPMC5466868
OpenAlexW2593599798

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.