Statins × inflammation & biomarkers

SynthesisLipids in health and disease2017

Effects of simvastatin on serum adiponectin: a meta-analysis of randomized controlled trials.

Weibin Chen et al.PubMed ↗Full text ↗Publisher ↗

  • Simvastatinno clear effectNo clear effect on serum adiponectin.Nothing cleared the noise.

What the trial testedas reported · 1,042 people · 2017

Range includes no effect

No clear effect on serum adiponectin

+0.42−0.66 to +1.50

simvastatin vs control

As reported

difference 0.42, 95% CI −0.66 to 1.50

Who was studied, and how

1,042people with cardiovascular disease, in this paper

The trial randomly assignedassigned by chance

simvastatin
control

No clear effect on serum adiponectin+0.42

randomised

the abstract, start to end

affected by simvastatin (WMD: 0.42 μg/mL; 95% CI, -0.66-1.50

← favours treatmentfavours comparator →
could be chance
Serum adiponectinsimvastatin vs control
0.42−0.66 to 1.50
StatinsInflammation & biomarkers

Statins × inflammation & biomarkershelps?mixed

unlikelylikely
0.48not counted
← favours treatmentfavours comparator →
more certainless certain
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3 papers cite it

2017
2018
2019
2020
this paperpooled itcites it
Full record →Abstract, authors, funding and every citing paper · PMID 28288631