Evidence map›Paper›PMID 28325813›Full record

ArticleG3 (Bethesda, Md.)2017

Aging Effects of

Baines K Nicoll, Célia Ferreira, Philip M Hopkins, Marie-Anne Shaw, Ian A Hope

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Baines K NicollLeeds Institute of Biomedical and Clinical Sciences, St James's University Hospital, LS9 7TF, United Kingdom bsknb@leeds.ac.uk M.Shaw@leeds.ac.uk i.a.hope@leeds.ac.uk.
Célia FerreiraSchool of Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT, United Kingdom.ORCID 0000-0003-1190-4323
Philip M HopkinsLeeds Institute of Biomedical and Clinical Sciences, St James's University Hospital, LS9 7TF, United Kingdom.ORCID 0000-0002-8127-1739
Marie-Anne ShawLeeds Institute of Biomedical and Clinical Sciences, St James's University Hospital, LS9 7TF, United Kingdom bsknb@leeds.ac.uk M.Shaw@leeds.ac.uk i.a.hope@leeds.ac.uk.
Ian A HopeSchool of Biology, Faculty of Biological Sciences, University of Leeds, LS2 9JT, United Kingdom bsknb@leeds.ac.uk M.Shaw@leeds.ac.uk i.a.hope@leeds.ac.uk.ORCID 0000-0002-8990-3163
St James's University Hospital · GBUniversity of Leeds · GB

Funding

Biotechnology and Biological Sciences Research Council BB/M00032X/1
6 · The paper itself

Abstract

Delaying the decline in skeletal muscle function will be critical to better maintenance of an active lifestyle in old age. The skeletal muscle ryanodine receptor, the major intracellular membrane channel through which calcium ions pass to elicit muscle contraction, is central to calcium ion balance and is hypothesized to be a significant factor for age-related decline in muscle function. The nematode

Indexed as

MutationAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsHumansLongevityMuscle, SkeletalMuscular DiseasesNeuronsPhenotypeRyanodine Receptor Calcium Release ChannelCaenorhabditis elegans ProteinsRyanodine Receptor Calcium Release ChannelUnc-68 protein, C elegansagingCaenorhabditis elegansmalignant hyperthermiamuscleryanodine receptor

Identifiers

PMID28325813
PMCPMC5427508
OpenAlexW2597746365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.