Evidence map›Paper›PMID 28325838›Full record

ArticleThe Journal of biological chemistry2017

Signaling pathway for phagocyte priming upon encounter with apoptotic cells.

Saori Nonaka, Yuki Ando, Takuto Kanetani, Chiharu Hoshi, Yuji Nakai, Firzan Nainu, Kaz Nagaosa, Akiko Shiratsuchi, Yoshinobu Nakanishi

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Generating and working with Drosophila cell cultures: Current challenges and opportunities.Wiley interdisciplinary reviews. Developmental biology · 2019
    Review
  7. Die in pieces: How Drosophila sheds light on neurite degeneration and clearance.Journal of genetics and genomics = Yi chuan xue bao · 2019
    Review
  8. Review
  9. Article
  10. Phagocytosis Assay for Apoptotic Cells in Drosophila Embryos.Journal of visualized experiments : JoVE · 2017
    Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Saori NonakaFrom the Graduate School of Medical Sciences and.ORCID 0000-0003-2672-3082
Yuki AndoFrom the Graduate School of Medical Sciences and.
Takuto KanetaniFrom the Graduate School of Medical Sciences and.
Chiharu HoshiSchool of Pharmacy, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.
Yuji Nakaithe Institute for Food Sciences, Hirosaki University, Aomori, Aomori 038-0012, Japan, and.
Firzan NainuFrom the Graduate School of Medical Sciences and.ORCID 0000-0003-0989-4023
Kaz Nagaosathe Institute for Food Sciences, Hirosaki University, Aomori, Aomori 038-0012, Japan, and.ORCID 0000-0002-1695-2562
Akiko ShiratsuchiFrom the Graduate School of Medical Sciences and.ORCID 0000-0002-7811-4409
Yoshinobu NakanishiFrom the Graduate School of Medical Sciences and nakanaka@p.kanazawa-u.ac.jp.ORCID 0000-0002-8767-3587
Graduate School USA · USHirosaki University · JPKanazawa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phagocytic elimination of cells undergoing apoptosis is an evolutionarily conserved innate immune mechanism for eliminating unnecessary cells. Previous studies showed an increase in the level of engulfment receptors in phagocytes after the phagocytosis of apoptotic cells, which leads to the enhancement of their phagocytic activity. However, precise mechanisms underlying this phenomenon require further clarification. We found that the pre-incubation of a

Indexed as

ApoptosisSignal TransductionAnimalsCell LineCell NucleusCycloheximideCytoskeletal ProteinsDNADrosophila melanogasterDrosophila ProteinsHemocytesImmunity, InnateIntegrin alpha ChainsMembrane ProteinsOncogene Protein v-crkPhagocytesalpha PS3 integrin, DrosophilaCycloheximideCytoskeletal ProteinsDNADrosophila Proteinsdrpr protein, DrosophilaIntegrin alpha Chainsmbc protein, DrosophilaMembrane ProteinsOncogene Protein v-crkRepressor ProteinsTLL protein, DrosophilaapoptosisDrosophilagene regulationphagocytosissignal transductiontranscription repressor

Identifiers

PMID28325838
PMCPMC5427281
OpenAlexW2598454275

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.