Trial reportLancet (London, England)2017
Computerised interpretation of fetal heart rate during labour (INFANT): a randomised controlled trial.
Trial report in Lancet (London, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 5 syntheses or guidelines pooled it, 201 citations in OpenAlex.
- Effectiveness of intrapartum fetal surveillance to improve maternal and neonatal outcomes: a systematic review and network meta-analysis.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2021Pooled it
- Systematic Review of Intrapartum Fetal Heart Rate Spectral Analysis and an Application in the Detection of Fetal Acidemia.Frontiers in pediatrics · 2021Pooled it
- Access to routinely collected health data for clinical trials - review of successful data requests to UK registries.Trials · 2020Pooled it
- Monitoring Fetal Electroencephalogram Intrapartum: A Systematic Literature Review.Frontiers in pediatrics · 2020Pooled it
- Design Characteristics of Studies Reporting the Performance of Artificial Intelligence Algorithms for Diagnostic Analysis of Medical Images: Results from Recently Published Papers.Korean journal of radiology · 2019Pooled it
- Two-year follow-up of infant and maternal outcomes after planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): A randomised controlled trial.BJOG : an international journal of obstetrics and gynaecology · 2022Trial
- Economic evaluation of computerised interpretation of fetal heart rate during labour: a cost-consequence analysis alongside the INFANT study.Archives of disease in childhood. Fetal and neonatal edition · 2021Trial
- Effect of Machine Learning on Dispatcher Recognition of Out-of-Hospital Cardiac Arrest During Calls to Emergency Medical Services: A Randomized Clinical Trial.JAMA network open · 2021Trial
- Effectiveness of a Novel Continuous Doppler (Moyo) Versus Intermittent Doppler in Intrapartum Detection of Abnormal Foetal Heart Rate: A Randomised Controlled Study in Tanzania.International journal of environmental research and public health · 2019Trial
- Enhancing agreement in cardiotocography interpretation between midwives and obstetricians through a rule-based AI program: A comparative cross-sectional study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Multicenter Usability Evaluation and Co-Development of a Digital Decision-Support Tool for Labor Triage: Mixed Methods Study.JMIR human factors · 2026Article
- Artificial intelligence-based prediction of fetal hypoxia: a multicenter model development and nationwide AI-human comparison.BMC medicine · 2026Article
- Patient and public involvement (PPI) reporting in maternal and neonatal clinical trials: an exploratory review.Trials · 2026Review
- Predicting Intrapartum Acidemia: A Review of Approaches Based on Fetal Heart Rate.Bioengineering (Basel, Switzerland) · 2026Review
- Recruitment, retention and reporting of ethnic representativeness in maternity trials: a scoping review.BMJ open · 2025Article
- Generational Leaps in Intrapartum Fetal Surveillance.Diagnostics (Basel, Switzerland) · 2025Review
- Improving UK data on avoidable perinatal brain injury: review of data dictionaries and consultation.Pediatric research · 2025Review
- Impact of missing electronic fetal monitoring signals on perinatal asphyxia: a multicohort analysis.NPJ digital medicine · 2025Article
- MRI-based artificial intelligence models for post-neoadjuvant surgery personalization in breast cancer: a narrative review of evidence from Western Pacific.The Lancet regional health. Western Pacific · 2025Review
- Dimensions of Human-Machine Combination: Prompting the Development of Deployable Intelligent Decision Systems for Situated Clinical Contexts.Computer supported cooperative work : CSCW : an international journal · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author at 8 institutions in 3 countries.
Funding
Abstract
backgroundContinuous electronic fetal heart-rate monitoring is widely used during labour, and computerised interpretation could increase its usefulness. We aimed to establish whether the addition of decision-support software to assist in the interpretation of cardiotocographs affected the number of poor neonatal outcomes.
methodsIn this unmasked randomised controlled trial, we recruited women in labour aged 16 years or older having continuous electronic fetal monitoring, with a singleton or twin pregnancy, and at 35 weeks' gestation or more at 24 maternity units in the UK and Ireland. They were randomly assigned (1:1) to decision support with the INFANT system or no decision support via a computer-generated stratified block randomisation schedule. The primary outcomes were poor neonatal outcome (intrapartum stillbirth or early neonatal death excluding lethal congenital anomalies, or neonatal encephalopathy, admission to the neonatal unit within 24 h for ≥48 h with evidence of feeding difficulties, respiratory illness, or encephalopathy with evidence of compromise at birth), and developmental assessment at age 2 years in a subset of surviving children. Analyses were done by intention to treat. This trial is completed and is registered with the ISRCTN Registry, number 98680152.
findingsBetween Jan 6, 2010, and Aug 31, 2013, 47 062 women were randomly assigned (23 515 in the decision-support group and 23 547 in the no-decision-support group) and 46 042 were analysed (22 987 in the decision-support group and 23 055 in the no-decision-support group). We noted no difference in the incidence of poor neonatal outcome between the groups-172 (0·7%) babies in the decision-support group compared with 171 (0·7%) babies in the no-decision-support group (adjusted risk ratio 1·01, 95% CI 0·82-1·25). At 2 years, no significant differences were noted in terms of developmental assessment.
interpretationUse of computerised interpretation of cardiotocographs in women who have continuous electronic fetal monitoring in labour does not improve clinical outcomes for mothers or babies.
fundingNational Institute for Health Research.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.