Evidence mapPaperPMID 28348175Full record

ReviewCold Spring Harbor perspectives in medicine2017

Omics and Exercise: Global Approaches for Mapping Exercise Biological Networks.

Nolan J Hoffman

Registry-linked trialAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05359744 (A Pilot-study on Multi-level Molecular Profiling of Peak Performance in Endurance Sports), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05359744 nacompletednot on this mapstarted 2021, after this paper: background citation

A Pilot-study on Multi-level Molecular Profiling of Peak Performance in Endurance Sports

TypeinterventionalSponsorParacelsus Medical UniversityRan2021 to 2022Enrolled80ConditionsExercise, Exercise Test, Physical Fitness, HealthyArmsPerformance testing
3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Molecular origin and biological effects of exercise mimetics.Journal of exercise science and fitness · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Nolan J HoffmanCentre for Exercise and Nutrition, Mary MacKillop Institute for Health Research, Australian Catholic University, Melbourne, Victoria 3000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of global "-omics" technologies to exercise has introduced new opportunities to map the complexity and interconnectedness of biological networks underlying the tissue-specific responses and systemic health benefits of exercise. This review will introduce major research tracks and recent advancements in this emerging field, as well as critical gaps in understanding the orchestration of molecular exercise dynamics that will benefit from unbiased omics investigations. Furthermore, significant research hurdles that need to be overcome to effectively fill these gaps related to data collection, computation, interpretation, and integration across omics applications will be discussed. Collectively, a cross-disciplinary physiological and omics-based systems approach will lead to discovery of a wealth of novel exercise-regulated targets for future mechanistic validation. This frontier in exercise biology will aid the development of personalized therapeutic strategies to improve athletic performance and human health through precision exercise medicine.

Indexed as

AnimalsBiomedical ResearchExerciseGenomicsHumansMetabolomePrecision MedicineTranscriptome

Identifiers

PMID28348175
PMCPMC5629985

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.