Evidence map›Paper›PMID 28351967›Full record

ArticlePhysiological reports2017

Concerted regulation of renal plasma flow and glomerular filtration rate by renal dopamine and NOS I in rats on high salt intake.

Mariano E Ibarra, Maria F Albertoni Borghese, Mónica P Majowicz, María C Ortiz, Fabián Loidl, Manuel Rey-Funes, Luis A Di Ciano, Fernando R Ibarra

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Renal Dopamine Oxidation and Inflammation in High Salt Fed Rats.Journal of the American Heart Association · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mariano E IbarraLaboratorio de Neuropatología Experimental, Instituto de Biología Celular y Neurociencia "Prof. E. De Robertis" (IBCN), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Maria F Albertoni BorgheseCátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Mónica P MajowiczCátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
María C OrtizCátedra de Biología Celular y Molecular, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Fabián LoidlLaboratorio de Neuropatología Experimental, Instituto de Biología Celular y Neurociencia "Prof. E. De Robertis" (IBCN), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Manuel Rey-FunesLaboratorio de Neuropatología Experimental, Instituto de Biología Celular y Neurociencia "Prof. E. De Robertis" (IBCN), Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Luis A Di CianoLaboratorio de Riñón, Instituto de Investigaciones Médicas A. Lanari Universidad de Buenos Aires, Buenos Aires, Argentina.
Fernando R IbarraLaboratorio de Riñón, Instituto de Investigaciones Médicas A. Lanari Universidad de Buenos Aires, Buenos Aires, Argentina ibarraf@hotmail.com.
University of Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Under high sodium intake renal dopamine (DA) increases while NOS I expression in macula densa cells (MD) decreases. To explore whether renal DA and NOS I, linked to natriuresis and to the stability of the tubuloglomerular feedback, respectively, act in concert to regulate renal plasma flow (RPF) and glomerular filtration rate (GFR). Male Wistar rats were studied under a normal sodium intake (NS, NaCl 0.24%) or a high sodium intake (HS, NaCl 1% in drinking water) during the 5 days of the study. For the last two days, the specific D

Indexed as

Sodium, DietaryAnimalsBenzazepinesBlood PressureDopamineDopamine AntagonistsGlomerular Filtration RateKidney CortexMaleNADPNatriuresisNitric Oxide Synthase Type IRatsRats, WistarRenal Plasma FlowSodium ChlorideBenzazepinesDopamineDopamine AntagonistsNADPNitric Oxide Synthase Type INos1 protein, ratSCH 23390Sodium ChlorideSodium, DietaryHigh salt intakeNOS I in MDRegulation of Renal Plasma FlowRenal Dopamine

Identifiers

PMID28351967
PMCPMC5371567
OpenAlexW2602942175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.