Evidence map›Paper›PMID 28356355›Full record

ArticleThe Journal of biological chemistry2017

Metabolomic profiling reveals a finely tuned, starvation-induced metabolic switch in

María Julia Barisón, Ludmila Nakamura Rapado, Emilio F Merino, Elizabeth Mieko Furusho Pral, Brian Suarez Mantilla, Letícia Marchese, Cristina Nowicki, Ariel Mariano Silber, Maria Belen Cassera

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
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  4. Review
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  8. Stage-specific MCM protein expression inFrontiers in cellular and infection microbiology · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Frontiers in molecular biosciences · 2023
    Article
  13. Article
  14. Hypoxia Effects onPathogens (Basel, Switzerland) · 2022
    Article
  15. Metabolic Alteration ofPathogens (Basel, Switzerland) · 2022
    Article
  16. AParasitology · 2021
    Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

María Julia BarisónFrom the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil.
Ludmila Nakamura RapadoFrom the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil.
Emilio F Merinothe Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, and.
Elizabeth Mieko Furusho PralFrom the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil.
Brian Suarez MantillaFrom the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil.
Letícia MarcheseFrom the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil.
Cristina Nowickithe Facultad de Farmacia y Bioquímica, Instituto de Química y Fisicoquímica Biológica (IQUIFIB-CONICET), Universidad de Buenos Aires, 1113 Buenos Aires, Argentina.
Ariel Mariano SilberFrom the Laboratory of Biochemistry of Tryps-LaBTryps, Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, 05508-000 São Paulo, Brazil, asilber@usp.br.
Maria Belen Casserathe Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Tech, Blacksburg, Virginia 24061, and maria.cassera@uga.edu.
Universidade de São Paulo · BRVirginia Tech · USConsejo Nacional de Investigaciones Científicas y Técnicas · AR

Funding

Characterization of isoprenoid biosynthesis in human malaria gametocytesR01AI108819 · NIAID · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI CASSERA, MARIA BELEN · 2014 to 2018
$1.9M
NIAID NIH HHS R01 AI108819
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Life Cycle StagesMetabolomeMetabolomicsTrypanosoma cruzicell growthcell metabolismChagas diseaseenergy metabolismepimastigotesmetabolomicsoxidative imbalanceTrypanosoma cruzi

Identifiers

PMID28356355
PMCPMC5448128
OpenAlexW2602442885

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.