Evidence map›Paper›PMID 28381826›Full record

ArticleScientific reports2017

Recombinant tandem of pore-domains in a Weakly Inward rectifying K

Nicole Bobak, Sylvain Feliciangeli, Cheng-Chang Chen, Ismail Ben Soussia, Stefan Bittner, Sophie Pagnotta, Tobias Ruck, Martin Biel, Christian Wahl-Schott, Christian Grimm and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 40 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Structure of the human TWIK-2 potassium channel and its inhibition by pimozide.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  6. Review
  7. Extracellular histones promote TWIK2-dependent potassium efflux and associated NLRP3 activation in alveolar macrophages during sepsis-induced lung injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article
  8. The ion channels of endomembranes.Physiological reviews · 2024
    Review
  9. Differential contribution of THIK-1 KJournal of neuroinflammation · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Lysosomal Potassium Channels.Handbook of experimental pharmacology · 2023
    Review
  16. Lysosomal solute and water transport.The Journal of cell biology · 2022
    Review
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Nicole BobakUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, LabEx ICST, 660 Route des Lucioles, 06560, Valbonne, France.
Sylvain FeliciangeliUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, LabEx ICST, 660 Route des Lucioles, 06560, Valbonne, France.
Cheng-Chang ChenCenter for Integrated Protein Science CIPS-M and Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, München, Germany.
Ismail Ben SoussiaUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, LabEx ICST, 660 Route des Lucioles, 06560, Valbonne, France.
Stefan BittnerDepartment of Neurology, University Medical Center of the Johannes Gutenberg-University Mainz, 55131, Mainz, Germany.
Sophie PagnottaCentre Commun de Microscopie Appliquée, Université Nice Sophia Antipolis, Nice, France.
Tobias RuckDepartment of Neurology, University of Münster, Albert-Schweizer Campus 1, 48149, Münster, Germany.
Martin BielCenter for Integrated Protein Science CIPS-M and Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, München, Germany.
Christian Wahl-SchottCenter for Integrated Protein Science CIPS-M and Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, München, Germany.
Christian GrimmCenter for Integrated Protein Science CIPS-M and Department of Pharmacy - Center for Drug Research, Ludwig-Maximilians-Universität München, München, Germany.
Sven G MeuthDepartment of Neurology, University of Münster, Albert-Schweizer Campus 1, 48149, Münster, Germany.
Florian LesageUniversité Côte d'Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, LabEx ICST, 660 Route des Lucioles, 06560, Valbonne, France. lesage@ipmc.cnrs.fr.ORCID http://orcid.org/0000-0002-4406-7106
Center for Integrated Protein Science Munich · DECentre National de la Recherche Scientifique · FRUniversity of Münster · DEJohannes Gutenberg University Mainz · DEUniversité Côte d'Azur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recombinant TWIK2 channels produce weak basal background K

Indexed as

Protein Interaction Domains and MotifsProtein MultimerizationRecombinant ProteinsAmino Acid SequenceAnimalsDogsGene ExpressionHEK293 CellsHumansLysosomesMadin Darby Canine Kidney CellsMicePotassium Channels, Tandem Pore DomainProtein TransportRatsKcnk6 protein, mousePotassium Channels, Tandem Pore DomainRecombinant Proteins

Identifiers

PMID28381826
PMCPMC5428834
OpenAlexW2602568323

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.