Evidence map›Paper›PMID 28396709›Full record

ArticleBiomicrofluidics2017

Human iPSC-derived myocardium-on-chip with capillary-like flow for personalized medicine.

Bradley W Ellis, Aylin Acun, U Isik Can, Pinar Zorlutuna

Abstract read
In one paragraph

Article in Biomicrofluidics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed.

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  7. Advancements in theFrontiers in toxicology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bradley W EllisBioengineering Graduate Program, University of Notre Dame , Notre Dame, Indiana 46556, USA.
Aylin AcunBioengineering Graduate Program, University of Notre Dame , Notre Dame, Indiana 46556, USA.
U Isik CanAerospace and Mechanical Engineering Department, University of Notre Dame , Notre Dame, Indiana 46556, USA.
Pinar Zorlutuna

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Development of Capillary-on-Chip for the Study of Preservation Injury on Microvascular Endothelial CellsF32HL176334 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Bradley Wayne Ellis · 2024 to 2026
$242k
NCATS NIH HHS UL1 TR001108NHLBI NIH HHS F32 HL176334
6 · The paper itself

Abstract

The heart wall tissue, or the myocardium, is one of the main targets in cardiovascular disease prevention and treatment. Animal models have not been sufficient in mimicking the human myocardium as evident by the very low clinical translation rates of cardiovascular drugs. Additionally, current

Identifiers

PMID28396709
PMCPMC5367145

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.