Evidence map›Paper›PMID 28401670›Full record

ArticleAddiction biology2018

Adolescents' behavioral and neural responses to e-cigarette advertising.

Yvonnes Chen, Carina H Fowler, Vlad B Papa, Rebecca J Lepping, Morgan G Brucks, Andrew T Fox, Laura E Martin

Abstract read
In one paragraph

Article in Addiction biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. The role of the orbitofrontal cortex in smoking cue-reactivity in onset phase of smoking behavior, a fMRI study in adolescents.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2026
    Article
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  20. E-Cigarette Marketing and Communication: How E-Cigarette Companies Market E-Cigarettes and the Public Engages with E-cigarette Information.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yvonnes ChenWilliam Allen White School of Journalism and Mass Communications, University of Kansas, Lawrence, KS, USA.ORCID 0000-0002-2569-7719
Carina H FowlerDepartment of Psychology and Neuroscience, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-4563-7756
Vlad B PapaHoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, USA.ORCID 0000-0001-8542-1039
Rebecca J LeppingHoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, USA.ORCID 0000-0001-9269-051X
Morgan G BrucksHoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, USA.ORCID 0000-0002-3212-0811
Andrew T FoxHoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, USA.ORCID 0000-0002-5603-2939
Laura E MartinHoglund Brain Imaging Center, University of Kansas Medical Center, Kansas City, KS, USA.ORCID 0000-0002-9800-9278
University of Kansas Medical Center · USUniversity of Kansas · USUniversity of North Carolina at Chapel Hill · US

Funding

Transgenic & Gene-Targeting Shared ResourceP30CA168524 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI ROY A. JENSEN · 2012 to 2026
$40.1M
Heartland Institute for Clinical and Translational ResearchUL1TR000001 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2012 to 2015
$13.0M
Siemens Magnetom Verio MRI ScannerS10RR029577 · NCRR · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BROOKS, WILLIAM M. · 2010 to 2010
$2.9M
NCATS NIH HHS UL1 TR000001NCI NIH HHS P30 CA168524NCRR NIH HHS S10 RR029577
6 · The paper itself

Abstract

Although adolescents are a group heavily targeted by the e-cigarette industry, research in cue-reactivity has not previously examined adolescents' behavioral and neural responses to e-cigarette advertising. This study addressed this gap through two experiments. In Experiment One, adult traditional cigarette smokers (n = 41) and non-smokers (n = 41) answered questions about e-cigarette and neutral advertising images. The 40 e-cigarette advertising images that most increased desire to use the product were matched to 40 neutral advertising images with similar content. In Experiment Two, the 80 advertising images selected in Experiment One were presented to adolescents (n = 30) during an functional magnetic resonance imaging brain scan. There was a range of traditional cigarette smoking across the sample with some adolescents engaging in daily smoking and others who had never smoked. Adolescents self-reported that viewing the e-cigarette advertising images increased their desire to smoke. Additionally, all participants regardless of smoking statuses showed significantly greater brain activation to e-cigarette advertisements in areas associated with cognitive control (left middle frontal gyrus), reward (right medial frontal gyrus), visual processing/attention (left lingual gyrus/fusiform gyrus, right inferior parietal lobule, left posterior cingulate, left angular gyrus) and memory (right parahippocampus, left insula). Further, an exploratory analysis showed that compared with age-matched non-smokers (n = 7), adolescent smokers (n = 7) displayed significantly greater neural activation to e-cigarette advertising images in the left inferior temporal gyrus/fusiform gyrus, compared with their responses to neutral advertising images. Overall, participants' brain responses to e-cigarette advertisements suggest a need to further investigate the long-run impact of e-cigarette advertising on adolescents.

Indexed as

Adolescent BehaviorAdvertisingElectronic Nicotine Delivery SystemsAdolescentBrainCuesFemaleFunctional NeuroimagingGyrus CinguliHumansMagnetic Resonance ImagingMaleNon-SmokersOccipital LobeParietal LobePrefrontal Cortexadolescentsadvertisingcue reactivityE-cigarettesfMRI

Identifiers

PMID28401670
PMCPMC5636647
OpenAlexW2605792243

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.