Evidence map›Paper›PMID 28410007›Full record

ReviewSmall GTPases2019

Key roles of Arf small G proteins and biosynthetic trafficking for animal development.

Francisco F Rodrigues, Tony J C Harris

Abstract readReview
In one paragraph

Review in Small GTPases, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Frontiers in cell and developmental biology · 2021
    Review
  10. Article
  11. ARF family GTPases with links to cilia.American journal of physiology. Cell physiology · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Francisco F RodriguesDepartment of Cell & Systems Biology, University of Toronto , Toronto , Ontario , Canada.
Tony J C HarrisDepartment of Cell & Systems Biology, University of Toronto , Toronto , Ontario , Canada.ORCID 0000-0002-0798-970X

Funding

CIHR MOP82829
6 · The paper itself

Abstract

Although biosynthetic trafficking can function constitutively, it also functions specifically for certain developmental processes. These processes require either a large increase to biosynthesis or the biosynthesis and targeted trafficking of specific players. We review the conserved molecular mechanisms that direct biosynthetic trafficking, and discuss how their genetic disruption affects animal development. Specifically, we consider Arf small G proteins, such as Arf1 and Sar1, and their coat effectors, COPI and COPII, and how these proteins promote biosynthetic trafficking for cleavage of the

Indexed as

ADP-Ribosylation FactorsAnimalsBone DevelopmentEmbryonic DevelopmentHumansNeurogenesisProtein BiosynthesisProtein TransportADP-Ribosylation Factorsanimal developmentArf GAPs; Arf GEFsArf small G proteinsbiosynthetic traffickingendoplasmic reticulumGolgi apparatusvesicle coat proteins

Identifiers

PMID28410007
PMCPMC6748413

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.