Evidence map›Paper›PMID 28424352›Full record

ArticleGenome research2017

Chromatin module inference on cellular trajectories identifies key transition points and poised epigenetic states in diverse developmental processes.

Sushmita Roy, Rupa Sridharan

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Chromatin Hubs: A biological and computational outlook.Computational and structural biotechnology journal · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Modeling the Hematopoietic Landscape.Frontiers in cell and developmental biology · 2019
    Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sushmita RoyDepartment of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, Wisconsin 53715, USA.
Rupa SridharanWisconsin Institute for Discovery, Madison, Wisconsin 53715, USA.
University of Wisconsin–Madison · USWisconsin Institutes for Discovery · US

Funding

TrainingU54AI117924 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI CRAVEN, MARK W. · 2014 to 2018
$11.3M
R01 Renewal: Collaboration of chromatin remodeling and signaling pathways in pluripotencyR01GM113033 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SRIDHARAN, RUPA · 2015 to 2023
$2.9M
Computational Inference of Regulatory Network Dynamics on Cell LineagesR01GM117339 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI ROY, SUSHMITA · 2016 to 2020
$1.5M
NIAID NIH HHS U54 AI117924NIGMS NIH HHS R01 GM113033NIGMS NIH HHS R01 GM117339
6 · The paper itself

Abstract

Changes in chromatin state play important roles in cell fate transitions. Current computational approaches to analyze chromatin modifications across multiple cell types do not model how the cell types are related on a lineage or over time

Indexed as

Cellular ReprogrammingEpigenesis, GeneticHematopoiesisCell LineChromatinHumansInduced Pluripotent Stem CellsChromatin

Identifiers

PMID28424352
PMCPMC5495076
OpenAlexW2605780550

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.