Evidence map›Paper›PMID 28442492›Full record

ArticleJournal of the American Society of Nephrology : JASN2017

Endothelin-A Receptor Antagonism Retards the Progression of Murine Sickle Cell Nephropathy.

Karl A Nath, Zvonimir S Katusic

Open access · greenAbstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Endothelin-1 signaling in the kidney: recent advances and remaining gaps.American journal of physiology. Renal physiology · 2025
    Review
  2. Chronic organ failure in adult sickle cell disease.Hematology. American Society of Hematology. Education Program · 2017
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Karl A NathDivision of Nephrology and Hypertension and Department of Medicine and nath.karl@mayo.edu.
Zvonimir S KatusicDepartments of Anesthesiology and.
Hypertension Institute · USWinnMed · US

Funding

Renal Injury and Adaptation to Heme ProteinsR37DK047060 · NIDDK · MAYO CLINIC ROCHESTER · PI NATH, KARL A. · 2002 to 2011
$3.6M
Mechanism of Dialysis Arteriovenous Fistula DysfunctionR01DK070124 · NIDDK · MAYO CLINIC ROCHESTER · PI NATH, KARL A. · 2005 to 2015
$3.4M
RENAL INJURY AND ADAPTATION TO HEME PROTEINSR01DK047060 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI NATH, KARL A. · 1993 to 2018
$2.2M
NIDDK NIH HHS R01 DK047060NIDDK NIH HHS R01 DK070124NIDDK NIH HHS R37 DK047060
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anemia, Sickle CellKidney DiseasesAnimalsEndothelin A Receptor AntagonistsEndothelinsMiceReceptor, Endothelin AEndothelin A Receptor AntagonistsEndothelinsReceptor, Endothelin Aendothelinhemehemoglobin Shemolysiskidneysickle cell disease

Identifiers

PMID28442492
PMCPMC5533247
OpenAlexW2607626602

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.