Evidence map›Paper›PMID 28446644›Full record

Trial reportNeurology2017

Body mass index and outcome after revascularization for symptomatic carotid artery stenosis.

Eline J Volkers, Jacoba P Greving, Jeroen Hendrikse, Ale Algra, L Jaap Kappelle, Jean-Pierre Becquemin, Leo H Bonati, Thomas G Brott, Richard Bulbulia, David Calvet and 11 more

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Body Mass Index and Late Adverse Outcomes after a Carotid Endarterectomy.International journal of environmental research and public health · 2023
    Article
  7. Article
  8. Review
  9. Carotid Revascularization: Current Practice and Future Directions.Seminars in interventional radiology · 2020
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

Eline J VolkersFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany. E.J.Volkers@umcutrecht.nl.
Jacoba P GrevingFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Jeroen HendrikseFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Ale AlgraFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
L Jaap KappelleFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Jean-Pierre BecqueminFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Leo H BonatiFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Thomas G BrottFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Richard BulbuliaFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
David CalvetFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Hans-Henning EcksteinFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Gustav FraedrichFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
John GregsonFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Alison HallidayFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
George HowardFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Olav JansenFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Gary S RoubinFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Martin M BrownFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Jean-Louis MasFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Peter A RinglebFrom the Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus (E.J.V., A.A., L.J.K.), Julius Center for Health Sciences and Primary Care (E.J.V., J.P.G., A.A.), and Department of Radiology (J.H.), University Medical Center Utrecht, the Netherlands; IVPE (J.-P.B.), Hopital Privé Paul D'Egine Champigny, France; Department of Neurology and Stroke Center (L.H.B.), University Hospital Basel, Switzerland; Department of Brain Repair and Rehabilitation (L.H.B., M.M.B.), UCL Institute of Neurology, University College London, UK; Department of Neurology (T.G.B.), Mayo Clinic, Jacksonville, FL; Clinical Trial Service Unit and Epidemiological Studies Unit (R.B.), Oxford University, UK; Department of Neurology (D.C., J.-L.M.), Hôpital Sainte-Anne, Université Paris-Descartes, DHU Neurovasc Sorbonne Paris Cité, INSERM U894, Paris, France; Department of Vascular and Endovascular Surgery/Vascular Center (H.-H.E.), Klinikum rechts der Isar, Technical University Munich, Germany; Department of Vascular Surgery (G.F.), Medical University of Innsbruck, Austria; London School for Hygiene and Tropical Medicine (J.G.); Nuffield Department of Surgical Sciences (A.H.), John Radcliffe Hospital, Oxford, UK; Department of Biostatistics (G.H.), UAB School of Public Health, Birmingham, AL; Clinic for Radiology and Neuroradiology (O.J.), UKSH Campus Kiel, Germany; Cardiovascular Associates of the Southeast (G.S.R.), Birmingham, AL; and Department of Neurology (P.A.R.), University of Heidelberg Medical School, Germany.
Carotid Stenosis Trialists' Collaboration
University Medical Center Utrecht · NL

Funding

Carotid Revascularization Endarterectomy vs Stenting TrialR01NS038384 · NINDS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI BROTT, THOMAS G · 1999 to 2010
$40.7M
Medical Research Council G0300411NINDS NIH HHS R01 NS038384
6 · The paper itself

Abstract

objectiveTo determine whether the obesity paradox exists in patients who undergo carotid artery stenting (CAS) or carotid endarterectomy (CEA) for symptomatic carotid artery stenosis.

methodsWe combined individual patient data from 2 randomized trials (Endarterectomy vs Angioplasty in Patients with Symptomatic Severe Carotid Stenosis and Stent-Protected Angioplasty vs Carotid Endarterectomy) and 3 centers in a third trial (International Carotid Stenting Study). Baseline body mass index (BMI) was available for 1,969 patients and classified into 4 groups: <20, 20-<25, 25-<30, and ≥30 kg/m

resultsMedian follow-up was 2.0 years. Stroke or death occurred in 159 patients in the periprocedural (cumulative risk 8.1%) and in 270 patients in the postprocedural period (rate 4.8/100 person-years). BMI did not affect periprocedural risk of stroke or death for patients assigned to CAS (

conclusionsBMI is not associated with periprocedural risk of stroke or death; however, BMI 25-<30 is associated with lower postprocedural risk than BMI 20-<25. These observations were similar for CAS and CEA.

Indexed as

AngioplastyBody Mass IndexEndarterectomy, CarotidAgedCarotid StenosisFemaleFollow-Up StudiesFunctional LateralityHumansMaleMultivariate AnalysisObesityProportional Hazards ModelsRiskSensitivity and SpecificityStents

Identifiers

PMID28446644
PMCPMC5440240
OpenAlexW2609576551

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.