Evidence map›Paper›PMID 28450399›Full record

ArticleThe Journal of biological chemistry2017

The crystal structure of mammalian inositol 1,3,4,5,6-pentakisphosphate 2-kinase reveals a new zinc-binding site and key features for protein function.

Elsa Franco-Echevarría, Julia Sanz-Aparicio, Charles A Brearley, Juana M González-Rubio, Beatriz González

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. mBio · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Elsa Franco-EchevarríaFrom the Departamento de Cristalografía y Biología Estructural, Instituto de Química-Física "Rocasolano," Consejo Superior de Investigaciones Científicas, Serrano 119, 28006 Madrid, Spain and.
Julia Sanz-AparicioFrom the Departamento de Cristalografía y Biología Estructural, Instituto de Química-Física "Rocasolano," Consejo Superior de Investigaciones Científicas, Serrano 119, 28006 Madrid, Spain and.
Charles A Brearleythe School of Biological Sciences, University of East Anglia, Norwich Research Park, Norwich NR4 7TJ, United Kingdom.
Juana M González-RubioFrom the Departamento de Cristalografía y Biología Estructural, Instituto de Química-Física "Rocasolano," Consejo Superior de Investigaciones Científicas, Serrano 119, 28006 Madrid, Spain and.
Beatriz GonzálezFrom the Departamento de Cristalografía y Biología Estructural, Instituto de Química-Física "Rocasolano," Consejo Superior de Investigaciones Científicas, Serrano 119, 28006 Madrid, Spain and xbeatriz@iqfr.csic.es.
Consejo Superior de Investigaciones Científicas · ESInstituto de Química Física Blas Cabrera · ESUniversity of East Anglia · GB

Funding

Biotechnology and Biological Sciences Research Council BB/N002024/1
6 · The paper itself

Abstract

Inositol 1,3,4,5,6-pentakisphosphate 2-kinases (IP

Indexed as

Adenosine TriphosphateAnimalsArabidopsisArabidopsis ProteinsBinding SitesCrystallography, X-RayInositol PhosphatesMicePhosphotransferases (Phosphate Group Acceptor)Structure-Activity RelationshipAdenosine TriphosphateArabidopsis Proteinsinositol hexakisphosphate kinaseInositol PhosphatesPhosphotransferases (Phosphate Group Acceptor)crystal structureenzyme mutationinositol hexakisphosphateinositol phosphateIP5 2-kinasestructure-functionzinc

Identifiers

PMID28450399
PMCPMC5481561
OpenAlexW2609079175

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.