GLP-1 receptor agonists × body weight & composition

TrialJournal of diabetes and its complications2017

Effect of weight reductions on estimated kidney function: Post-hoc analysis of two randomized trials.

Bernt Johan von Scholten et al.PubMed ↗Publisher ↗

  • Liraglutide 3.0mgno clear effectLower weight loss, no range given.No ranges given.
  • Placebono clear effectLower weight loss, no range given.No ranges given.

What the trial testedas reported · 9,154 people · 2017

No range given

Reported lower weight loss, no range given

−8.00

liraglutide 3.0mg vs placebo

As reported

difference −8.00, no interval

No range given

Reported lower weight loss, no range given

−2.60

placebo vs liraglutide 3.0mg

As reported

difference −2.60, no interval

No range given

Reported lower weight loss, no range given

−5.90

liraglutide 3.0mg vs placebo

As reported

difference −5.90, no interval

No range given

Reported lower weight loss, no range given

−2.00

placebo vs liraglutide 3.0mg

As reported

difference −2.00, no interval

+5 more in the walkthrough ↓

Who was studied, and how

9,154people with obesity, in this paper

The trial randomly assignedassigned by chance

liraglutide 3.0mg
placebo

Reported lower weight loss, no range given−8.00

randomised

The trial randomly assignedassigned by chance

placebo
liraglutide 3.0mg

Reported lower weight loss, no range given−2.60

randomised

the abstract, start to end

to week 56) with liraglutide was 8.0±6.7% (2.6±6.9% with placebo); baseline creatinine with liraglutide was 76±15μmol/L and 74±15μmol/L after 56weeks (similar

weight loss with liraglutide was 5.9±5.5% (2.0±4.3% with placebo); baseline creatinine was 79±19μmol/L (77±16μmol/L, placebo) and 79±20μmol/L after 56weeks (76±15μmol/L, placebo).

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Weight loss (baseline to week 56)liraglutide 3.0mg vs placebo
−8.00
Weight loss (baseline to week 56)placebo vs liraglutide 3.0mg
−2.60
Baseline creatinineliraglutide 3.0mg
76
Creatinine after 56 weeksliraglutide 3.0mg
74
Weight lossliraglutide 3.0mg vs placebo
−5.90
Weight lossplacebo vs liraglutide 3.0mg
−2.00
Baseline creatinineliraglutide 3.0mg
79
Baseline creatinineplacebo
77
Creatinine after 56 weeksplacebo
76
GLP-1 receptor agonistsBody weight & compositionKidney outcomes
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3 papers cite it

2017
2018
2019
2020
2021
2022
2023
2024
2025
this paperpooled ittrialcites it

2 trials

Full record →Abstract, authors, funding and every citing paper · PMID 28462892