Trial reportJournal of biological rhythms2017
Acute Effects of Morning Light on Plasma Glucose and Triglycerides in Healthy Men and Men with Type 2 Diabetes.
Trial report in Journal of biological rhythms, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 45 citations in OpenAlex.
- The effect of bright light therapy on glycemic control and cortisol rhythmicity in depression: a randomized controlled trial.Frontiers in psychiatry · 2026Trial
- The influence of bright and dim light on substrate metabolism, energy expenditure and thermoregulation in insulin-resistant individuals depends on time of day.Diabetologia · 2022Trial
- The effect of melatonin on glucose tolerance, insulin sensitivity and lipid profiles after a late evening meal in healthy young males.Journal of pineal research · 2021Trial
- Circadian rhythm amplification in diabetic retinopathy: a pilot study.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Exposure to artificial lighting at night: from an ecological challenge to a risk factor for glucose dysmetabolism and gestational diabetes? Narrative review.Annals of medicine · 2025Review
- The Acute Effects of Morning Bright Light on the Human White Adipose Tissue Transcriptome: Exploratory Post Hoc Analysis.Clocks & sleep · 2025Article
- Artificial Light at Night and Type 2 Diabetes Mellitus.Diabetes & metabolism journal · 2024Review
- The Role of the Circadian Rhythm in Dyslipidaemia and Vascular Inflammation Leading to Atherosclerosis.International journal of molecular sciences · 2023Review
- The Complex Effects of Light on Metabolism in Humans.Nutrients · 2023Review
- Circadian rhythms and pancreas physiology: A review.Frontiers in endocrinology · 2022Review
- Astrocyte Clocks and Glucose Homeostasis.Frontiers in endocrinology · 2021Review
- Relationship Between Circadian Strain, Light Exposure, and Body Mass Index in Rural and Urban Quilombola Communities.Frontiers in physiology · 2021Article
- Beneficial effects of daytime high-intensity light exposure on daily rhythms, metabolic state and affect.Scientific reports · 2020Article
- Metabolic Effects of Light at Night are Time- and Wavelength-Dependent in Rats.Obesity (Silver Spring, Md.) · 2020Article
- Metabolic Implications of Exposure to Light at Night: Lessons from Animal and Human Studies.Obesity (Silver Spring, Md.) · 2020Review
- Blue light at night acutely impairs glucose tolerance and increases sugar intake in the diurnal rodent Arvicanthis ansorgei in a sex-dependent manner.Physiological reports · 2019Article
- Sleep and Environmental Factors Affecting Glycemic Control in People with Type 2 Diabetes Mellitus.Current diabetes reports · 2019Review
- Circadian clocks and insulin resistance.Nature reviews. Endocrinology · 2019Review
- Effects of Light-at-Night on the Rat Liver - A Role for the Autonomic Nervous System.Frontiers in neuroscience · 2019Article
- A time to fast.Science (New York, N.Y.) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ambient light intensity is signaled directly to hypothalamic areas that regulate energy metabolism. Observational studies have shown associations between ambient light intensity and plasma glucose and lipid levels, but human data on the acute metabolic effects of light are scarce. Since light is the main signal indicating the onset of the diurnal phase of physical activity and food intake in humans, we hypothesized that bright light would affect glucose and lipid metabolism. Therefore, we determined the acute effects of bright light on plasma glucose and lipid concentrations in 2 randomized crossover trials: (1) in 8 healthy lean men and (2) in 8 obese men with type 2 diabetes. From 0730 h, subjects were exposed to either bright light (4000 lux) or dim light (10 lux) for 5 h. After 1 h of light exposure, subjects consumed a 600-kcal mixed meal. Primary endpoints were fasting and postprandial plasma glucose levels. In healthy men, bright light did not affect fasting or postprandial plasma glucose levels. However, bright light increased fasting and postprandial plasma triglycerides. In men with type 2 diabetes, bright light increased fasting and postprandial glucose levels. In men with type 2 diabetes, bright light did not affect fasting triglyceride levels but increased postprandial triglyceride levels. We show that ambient light intensity acutely affects human plasma glucose and triglyceride levels. Our findings warrant further research into the consequences of the metabolic effects of light for the diagnosis and prevention of hyperglycemia and dyslipidemia.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.