Trial reportJournal of diabetes and its complications2017
Dietary intake and risk of non-severe hypoglycemia in adolescents with type 1 diabetes.
Trial report in Journal of diabetes and its complications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01286350 (FL3X), which is not on this map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
FL3X: An Adaptive Intervention to Improve Outcomes for Youth With Type 1 Diabetes
Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- Effects of intake of four types of snack with different timings on postprandial glucose levels after dinner.European journal of nutrition · 2023Trial
- Dysglycemia among youth with type 1 diabetes and suboptimal glycemic control in the Flexible Lifestyle Empowering Change trial.Pediatric diabetes · 2019Trial
- The Interplay between Dietary Habits and Glycemic Control in Type 1 Diabetes: A Comprehensive Prospective FGM Study.Life (Basel, Switzerland) · 2024Article
- Pre-exercise protein intake is associated with reduced time in hypoglycaemia among adolescents with type 1 diabetes.Diabetes, obesity & metabolism · 2024Article
- The Impact of Medical Nutritional Therapy on the Efficacy of Premix Insulin in Glycemic Control in Patients with Type 2 Diabetes.Materia socio-medica · 2023Article
- Sedentary Behavior and Physical Activity Associated with Psychosocial Outcomes in Adolescents with Type 1 Diabetes.Pediatric diabetes · 2023Article
- Physical Activity, Dietary Patterns, and Glycemic Management in Active Individuals with Type 1 Diabetes: An Online Survey.International journal of environmental research and public health · 2021Article
- Impact of Fat Intake on Blood Glucose Control and Cardiovascular Risk Factors in Children and Adolescents with Type 1 Diabetes.Nutrients · 2021Review
- Technological Ecological Momentary Assessment Tools to Study Type 1 Diabetes in Youth: Viewpoint of Methodologies.JMIR diabetes · 2021Article
- Dietary intake and hospitalisation due to diabetic ketoacidosis and hypoglycaemia in individuals with type 1 diabetes.Scientific reports · 2021Article
- A machine-learning approach to predict postprandial hypoglycemia.BMC medical informatics and decision making · 2019Article
- Effects of the dietary approaches to stop hypertension (DASH) diet on glucose variability in youth with Type 1 diabetes.Diabetes management (London, England) · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 1 country.
Funding
Abstract
aimsTo determine the association between dietary intake and risk of non-severe hypoglycemia in adolescents with type 1 diabetes.
methodsType 1 adolescents from a randomized trial wore a blinded continuous glucose monitoring (CGM) system at baseline for one week in free-living conditions. Dietary intake was calculated as the average from two 24-h dietary recalls. Non-severe hypoglycemia was defined as having blood glucose <70mg/dL for ≥10min but not requiring external assistance, categorized as daytime and nocturnal (11PM-7AM). Data were analyzed using logistic regression models.
resultsAmong 98 participants with 14,277h of CGM data, 70 had daytime hypoglycemia, 66 had nocturnal hypoglycemia, 55 had both, and 17 had neither. Soluble fiber and protein intake were positively associated with both daytime and nocturnal hypoglycemia. Glycemic index, monounsaturated fat, and polyunsaturated fat were negatively associated with daytime hypoglycemia only. Adjusting for total daily insulin dose per kilogram eliminated all associations.
conclusionsDietary intake was differentially associated with daytime and nocturnal hypoglycemia. Over 80% of type 1 adolescents had hypoglycemia in a week, which may be attributed to the mismatch between optimal insulin dose needed for each meal and actually delivered insulin dose without considering quality of carbohydrate and nutrients beyond carbohydrate. CLINICAL
trial registrationClinicalTrials.gov identifier: NCT01286350.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.