ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019
Prediction of sudden cardiac death in patients with chronic heart failure by regional washout rate in cardiac MIBG SPECT imaging.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- The prognostic value ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Pooled it
- MIBG Scintigraphy and Arrhythmic Risk in Myocarditis.Biomedicines · 2025Article
- Cardiac imaging for the prediction of sudden cardiac arrest in patients with heart failure.Heliyon · 2023Review
- Modified Algorithm Using Total Count for Calculating Myocardial Washout Rate in Single-Photon Emission Computerized Tomography.Annals of nuclear cardiology · 2023Article
- CardiacPharmaceuticals (Basel, Switzerland) · 2022Review
- Advanced imaging for risk stratification for ventricular arrhythmias and sudden cardiac death.Frontiers in cardiovascular medicine · 2022Review
- Quality and utility of [Annals of nuclear medicine · 2021Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2019: Single-photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Review
- Assessing arrhythmic risk withJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Mechanisms supporting potential use of bone marrow-derived mesenchymal stem cells in psychocardiology.American journal of translational research · 2019Review
- Sudden cardiac death in patients with chronic heart failure: Rule of thumb in prediction studies.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017Article
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17 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe sympathetic nervous system provides an important trigger for major arrhythmic events through regional heterogeneity of sympathetic activity, which could be evaluated by SPECT imaging as the regional MIBG washout rate (WR). There is little information available on the prognostic value of regional WR in SPECT imaging for the prediction of sudden cardiac death (SCD) in patients with chronic heart failure (CHF).
methodsWe studied 73 CHF outpatients with LVEF < 40%. At study entry, the regional WR was measured in 17 segments on the polar map. We defined abnormal regional WR as both the regional WR range (maximum - minimum regional WR) and maximum regional WR > mean value + 2SD obtained in 15 normal controls.
resultsDuring a mean follow-up of 7.5 ± 4.1 years, 15 of 73 patients had SCD. The abnormal regional WR and abnormal global WR on planar images were significantly and independently associated with SCD. Patients with both the abnormal regional WR and global WR had a significantly higher risk of SCD than those with none of these criteria.
conclusionsThe analysis of regional MIBG WR on SPECT imaging provides additional prognostic value to global WR on planar images for SCD prediction in CHF patients.
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