Evidence map›Paper›PMID 28512126›Full record

ArticleThe Journal of biological chemistry2017

Tumor-associated myoepithelial cells promote the invasive progression of ductal carcinoma

Pang-Kuo Lo, Yongshu Zhang, Yuan Yao, Benjamin Wolfson, Justine Yu, Shu-Yan Han, Nadire Duru, Qun Zhou

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 60 citations in OpenAlex.

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  8. EMT and cancer: what clinicians should know.Nature reviews. Clinical oncology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Pang-Kuo LoFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and.
Yongshu ZhangFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and.
Yuan YaoFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and.
Benjamin WolfsonFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and.
Justine YuFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and.
Shu-Yan HanFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and.
Nadire DuruFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and.
Qun ZhouFrom the Department of Biochemistry and Molecular Biology, Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, Maryland 21201 and qzhou@som.umaryland.edu.
University of Maryland, Baltimore · USPeking University Cancer Hospital · CN

Funding

EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Training Grant in Cancer BiologyT32CA154274 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI Toni M Antalis, CURT I CIVIN · 2011 to 2026
$6.8M
miR-140 and Breast Cancer PreventionR01CA163820 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI ZHOU, QUN · 2012 to 2016
$1.6M
Shikonin and Nrf2 ChemopreventionR01CA157779 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI ZHOU, QUN · 2013 to 2017
$1.4M
NCI NIH HHS R01 CA157779NCI NIH HHS R01 CA163820NCI NIH HHS T32 CA154274NIGMS NIH HHS R25 GM055036
6 · The paper itself

Abstract

The normal myoepithelium has a tumor-suppressing nature and inhibits the progression of ductal carcinoma

Indexed as

Signal TransductionAnimalsBreast NeoplasmsCarcinoma, Intraductal, NoninfiltratingCell Line, TumorEpithelial CellsFemaleGene Expression Regulation, NeoplasticHeterograftsHumansMiceMice, NudeMicroRNAsMyeloid CellsNeoplasm InvasivenessNeoplasm ProteinsMicroRNAsNeoplasm ProteinsRNA, NeoplasmTransforming Growth Factor betabreast cancerepithelial-mesenchymal transition (EMT)microRNA (miRNA)transforming growth factor beta (TGFβ)tumor microenvironment

Identifiers

PMID28512126
PMCPMC5500811
OpenAlexW2616866590

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.