Evidence map›Paper›PMID 28535798›Full record

ArticleBMC neuroscience2017

Using Kalirin conditional knockout mice to distinguish its role in dopamine receptor mediated behaviors.

Taylor P LaRese, Yan Yan, Betty A Eipper, Richard E Mains

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. A Novel Cis-Regulatory lncRNA,Non-coding RNA · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Taylor P LaReseDepartment of Neuroscience, University of Connecticut Health Center, Farmington, CT, 06030-3401, USA.
Yan YanDepartment of Neuroscience, University of Connecticut Health Center, Farmington, CT, 06030-3401, USA.
Betty A EipperDepartment of Neuroscience, University of Connecticut Health Center, Farmington, CT, 06030-3401, USA.
Richard E MainsDepartment of Neuroscience, University of Connecticut Health Center, Farmington, CT, 06030-3401, USA. mains@uchc.edu.ORCID 0000-0003-1154-1331
UConn Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMice lacking Kalirin-7 (Kal7

resultsA comparison of the effects of experimenter-administered cocaine on mice lacking all Kalirin isoforms to its effects on mice lacking only Kalirin-7 identified Kal7 as the key isoform whose deletion produces exaggerated locomotor responses to cocaine. Pretreatment of Kal7

conclusionsThe cocaine-sensitive neuronal pathways which are most sensitive to altered Kalirin function may be the pathways most dependent on GluN2B and Drd2.

Indexed as

AnimalsBehavior, AnimalCocaineDopamine Uptake InhibitorsGuanine Nucleotide Exchange FactorsLocomotionMiceMice, KnockoutReceptors, DopamineReceptors, N-Methyl-D-AspartateCocaineDopamine Uptake InhibitorsGuanine Nucleotide Exchange FactorsKALRN protein, mouseNR2B NMDA receptorReceptors, DopamineReceptors, N-Methyl-D-AspartateAnxietyCre recombinaseGDP/GTP exchange factorGEFLocomotor sensitizationTrio

Identifiers

PMID28535798
PMCPMC5442696
OpenAlexW2619912801

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.