Evidence map›Paper›PMID 28550168›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017

Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.

Anto Sam Crosslee Louis Sam Titus, Tanzeen Yusuff, Marlène Cassar, Elizabeth Thomas, Doris Kretzschmar, Santosh R D'Mello

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
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  8. Case report: Expanding the phenotype ofFrontiers in neurology · 2023
    Article
  9. Article
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  11. Mitochondrial dysfunction and oxidative stress contribute to cognitive and motor impairment in FOXP1 syndrome.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Anto Sam Crosslee Louis Sam TitusDepartment of Molecular and Cell Biology, University of Texas at Dallas, Richardson, Texas 75080.ORCID 0000-0002-7608-6520
Tanzeen YusuffDepartment of Biological Sciences, Southern Methodist University, Dallas, Texas 75275.
Marlène CassarOregon Institute of Occupational Health Sciences, Oregon Health and Science University, Portland, Oregon 97239, and.ORCID 0000-0001-5335-4898
Elizabeth ThomasDepartment of Neuroscience, Scripps Research Institute, La Jolla, California 92037.
Doris KretzschmarOregon Institute of Occupational Health Sciences, Oregon Health and Science University, Portland, Oregon 97239, and.
Santosh R D'MelloDepartment of Molecular and Cell Biology, University of Texas at Dallas, Richardson, Texas 75080, sdmello@smu.edu.
Oregon Health & Science University · USThe University of Texas at Dallas · USScripps Research Institute · USSouthern Methodist University · US

Funding

Signaling Pathways Regulating Neuronal SurvivalR01NS040408 · NINDS · UNIVERSITY OF TEXAS DALLAS · PI D'MELLO, SANTOSH R · 2002 to 2018
$4.8M
NINDS NIH HHS R01 NS040408
6 · The paper itself

Abstract

Huntington's disease (HD) is an inherited neurodegenerative disease caused by a polyglutamine expansion in the huntington protein (

Indexed as

AnimalsBiomarkersCells, CulturedCerebral CortexCorpus StriatumDown-RegulationFemaleForkhead Transcription FactorsHumansHuntingtin ProteinHuntington DiseaseMaleMiceMice, Inbred C57BLMice, KnockoutMice, TransgenicBiomarkersForkhead Transcription FactorsFOXP1 protein, humanHTT protein, humanHuntingtin ProteinRepressor ProteinsFoxp1Huntington's diseaseneurodegenerationneuroprotection

Identifiers

PMID28550168
PMCPMC5511885
OpenAlexW2619387198

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.