Evidence map›Paper›PMID 28558160›Full record

Trial reportObesity (Silver Spring, Md.)2017

Randomized trial reveals that physical activity and energy expenditure are associated with weight and body composition after RYGB.

Elvis Alvarez Carnero, Gabriel S Dubis, Kazanna C Hames, John M Jakicic, Joseph A Houmard, Paul M Coen, Bret H Goodpaster

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Obesity (Silver Spring, Md.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04151836 (Effect of Exercise Intervention on Body Composition and Quality of Life in Post-bariatric Surgery Patients), which is not on this map. Cited by 34 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04151836 nacompletednot on this mapstarted 2020, after this paper: background citation

Effect of Exercise Intervention on Body Composition and Quality of Life in Post-bariatric Surgery Patients

TypeinterventionalSponsorChang Gung Memorial HospitalRan2020 to 2021Enrolled85ConditionsExerciseArmsExercise education
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Expert-based physical activity guidelines for metabolic and bariatric surgery patients: a systematic review of randomized controlled trials.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Effect of exercise training before and after bariatric surgery: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Physical training following gastric bypass: effects on physical activity and quality of life-a randomized controlled trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Trial
  10. Trial
  11. Review
  12. Observational
  13. Review
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  15. Review
  16. Article
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  18. Article
  19. Targeting skeletal muscle mitochondrial health in obesity.Clinical science (London, England : 1979) · 2022
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elvis Alvarez CarneroTranslational Research Institute for Metabolism and Diabetes, Florida Hospital, Orlando, Florida, USA.
Gabriel S DubisDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Kazanna C HamesDivision of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
John M JakicicDepartment of Health and Physical Activity, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Joseph A HoumardDepartment of Kinesiology, East Carolina University, Greenville, North Carolina, USA.
Paul M CoenDivision of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Bret H GoodpasterDivision of Endocrinology and Metabolism, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Funding

Physical Activity Following Surgery-Induced Weight LossR01DK078192 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GOODPASTER, BRET H · 2008 to 2012
$3.0M
NIDDK NIH HHS R01 DK078192
6 · The paper itself

Abstract

objectiveThis study investigated the associations of both physical activity time (PA) and energy expenditure (EE) with weight and fat mass (FM) loss in patients following Roux-en-Y gastric bypass (RYGB) surgery.

methodsNinety-six nondiabetic patients were included in this analysis. Post-RYGB patients were randomized in one of two treatments: A 6-month exercise training program (RYBG+EX) or lifestyle educational classes (RYGB). Body composition was assessed by dual-energy X-ray absorptiometry and computed tomography. Components of PA and EE were quantified by a multisensory device. Dose-response relationships of both PA and EE with weight loss and body composition were explored according to quartiles of change in steps per day.

resultsPatients in the highest quartiles of steps per day change lost more FM (3rd = -19.5 kg and 4th = -22.7 kg, P < 0.05) and abdominal adipose tissue (4th = -313 cm

conclusionsNondiabetic patients who perform higher, yet still modest, amounts of PA following RYGB have greater energy deficits and lose more weight and FM, while maintaining higher skeletal muscle mass.

Indexed as

Body CompositionBody WeightEnergy MetabolismExerciseGastric BypassAbsorptiometry, PhotonAdultCardiorespiratory FitnessDietFemaleHealth EducationHumansLife StyleMaleMiddle AgedObesity

Identifiers

PMID28558160
PMCPMC5513190

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.