Evidence map›Paper›PMID 28569359›Full record

Trial reportObesity surgery2017

Early Effects of Sleeve Gastrectomy on Obesity-Related Cytokines and Bile Acid Metabolism in Morbidly Obese Japanese Patients.

Hideharu Shimizu, Fumihiko Hatao, Kazuhiro Imamura, Kijuro Takanishi, Motoyoshi Tsujino

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Obesity surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04540263 (Evaluation of Blood Cytokine Levels of Patients Who Underwent Sleeve Gastrectomy and Gastric Bypass Operations Due to Obesity), which is not on this map. Cited by 16 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 4 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04540263 completednot on this mapstarted 2020, after this paper: background citation

Evaluation of Blood Cytokine Levels of Patients Who Underwent Sleeve Gastrectomy and Gastric Bypass Operations Due to Obesity

TypeobservationalSponsorIstanbul Training and Research HospitalRan2020 to 2021Enrolled30ConditionsObesityArmsFlow Cytometric analysis
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Review
  8. Review
  9. Impact of Bariatric Surgery on Adipose Tissue Biology.Journal of clinical medicine · 2021
    Review
  10. Article
  11. The immune remodel: Weight loss-mediated inflammatory changes to obesity.Experimental biology and medicine (Maywood, N.J.) · 2020
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hideharu ShimizuDepartment of Surgery, Tokyo Metropolitan Tama Medical Center, 2-8-29, Musashidai, Fuchu, Tokyo, Japan. hideharumaki@gmail.com.ORCID http://orcid.org/0000-0003-0039-3556
Fumihiko HataoDepartment of Surgery, Tokyo Metropolitan Tama Medical Center, 2-8-29, Musashidai, Fuchu, Tokyo, Japan.
Kazuhiro ImamuraDepartment of Surgery, Tokyo Metropolitan Tama Medical Center, 2-8-29, Musashidai, Fuchu, Tokyo, Japan.
Kijuro TakanishiDepartment of Surgery, Tokyo Metropolitan Tama Medical Center, 2-8-29, Musashidai, Fuchu, Tokyo, Japan.
Motoyoshi TsujinoDepartment of Endocrinology, Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo, 183-8524, Japan.
Tokyo Metropolitan Tama Medical Center · JP

Funding

Clinical Research Fund of Tokyo Metropolitan government H260502002
6 · The paper itself

Abstract

backgroundLaparoscopic sleeve gastrectomy (LSG) has wide-ranging positive effects on adipocytokine metabolism, bile acid profile, and chronic low-grade inflammation related to obesity. However, the early temporal changes in these markers following LSG have not been well investigated. This study aimed to evaluate the early effects of LSG on adipocytokines, bile acid profile, and inflammatory markers.

methodsThis was a nonrandomized prospective study examining morbidly obese Japanese patients undergoing LSG. Serial measurements of leptin, adiponectin, bile acids, fibroblast growth factor (FGF)-19, and inflammatory markers were performed preoperatively and 1 and 6 months after LSG.

resultsThe study included ten patients (five females) with a mean age of 48.8 years and BMI 40.9 kg/m

conclusionsLSG improved the secretion of adipocytokines, increased FGF-19 secretion soon after surgery, and slowly ameliorated inflammation related to obesity through significant weight loss.

Indexed as

GastrectomyAdipokinesAdultBile Acids and SaltsCytokinesFemaleFollow-Up StudiesHumansJapanLaparoscopyMaleMiddle AgedObesity, MorbidPostoperative PeriodTime FactorsWeight LossAdipokinesBile Acids and SaltsCytokinesAdipocytokineBile acidsInflammationSleeve gastrectomy

Identifiers

PMID28569359
OpenAlexW2617518779

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.