ArticleDrugs & aging2017
Medication Use and Fall-Related Hospital Admissions from Long-Term Care Facilities: A Hospital-Based Case-Control Study.
Article in Drugs & aging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.
- Potentially inappropriate prescribing and falls-risk increasing drugs in people who have experienced a fall: a systematic review and meta-analysis.Age and ageing · 2025Pooled it
- A systematic review of reasons and risks for acute service use by older adult residents of long-term care.Journal of clinical nursing · 2025Pooled it
- Medications and Prescribing Patterns as Factors Associated with Hospitalizations from Long-Term Care Facilities: A Systematic Review.Drugs & aging · 2018Pooled it
- Integrating Pharmacists Into Aged Care Vaccination: Strengthening Public Health Immunisation Systems Through the Aged Care on-Site Pharmacist Program (ACOP) in Australia.Australasian journal on ageing · 2026Article
- Arterial Stiffness Mechanisms and Orthostatic Hypotension in SPRINT: A Randomized Controlled Trial.JACC. Advances · 2026Article
- Relating consequential falls to individual and combinations of prescription medication use in Swedish older adults.European journal of clinical pharmacology · 2026Article
- Article
- Management of fall-risk-increasing drugs in Australian aged care residents: a retrospective cross-sectional study.BMC geriatrics · 2025Article
- Polypharmacy in older adults: a narrative review of definitions, epidemiology and consequences.European geriatric medicine · 2021Review
- Analysis of Fall Risk Factors in an Aging Population Living in Long-Term Care Institutions in SPAIN: A Retrospective Cohort Study.International journal of environmental research and public health · 2020Article
- Root cause analysis of fall-related hospitalisations among residents of aged care services.Aging clinical and experimental research · 2020Article
- Impact of Function Focused Care and Physical Activity on Falls in Assisted Living Residents.The Canadian journal of nursing research = Revue canadienne de recherche en sciences infirmieres · 2020Article
- Prevalence and Variability in Medications Contributing to Polypharmacy in Long-Term Care Facilities.Drugs - real world outcomes · 2017Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFalls are a leading cause of preventable hospitalizations from long-term care facilities (LTCFs). Polypharmacy and falls-risk medications are potentially modifiable risk factors for falling.
objectiveThis study investigated whether polypharmacy and falls-risk medications are associated with fall-related hospital admissions from LTCFs compared with hospital admissions for other causes.
methodsThis was a hospital-based, case-control study of patients aged ≥65 years hospitalized from LTCFs. Cases were patients with falls and fall-related injuries, and controls were patients admitted for infections. Conditional logistic regression was used to calculate adjusted odds ratios (ORs) and 95% confidence intervals (CIs) for the associations between polypharmacy (defined as the use of nine or more regular pre-admission medications) and falls-risk medications (categorized as psychotropic medications and those that can cause orthostatic hypotension) with fall-related hospital admissions.
resultsThere was no association between polypharmacy and fall-related hospital admissions (adjusted OR 0.97, 95% CI 0.63-1.48); however, the adjusted odds of fall-related hospital admissions increased by 16% (95% CI 3-30%) for each additional falls-risk medication. Medications that can cause orthostatic hypotension (adjusted OR 1.25, 95% CI 1.06-1.46), but not psychotropic falls-risk medications (adjusted OR 1.02, 95% CI 0.88-1.18) were associated with fall-related hospital admissions. The association between medications that can cause orthostatic hypotension and fall-related hospital admissions was strongest among residents with polypharmacy (adjusted OR 1.44, 95% CI 1.08-1.92).
conclusionPolypharmacy was not an independent risk factor for fall-related hospital admissions; however, medications that can cause orthostatic hypotension were associated with fall-related hospital admissions, particularly among residents with polypharmacy. Falls-risk should be considered when prescribing medications that can cause orthostatic hypotension.
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