Evidence map›Paper›PMID 28577984›Full record

ReviewBiochimica et biophysica acta. Reviews on cancer2017

Protein kinase D signaling in cancer: A friend or foe?

Adhiraj Roy, Jing Ye, Fan Deng, Qiming Jane Wang

Open access · greenAbstract readReview
In one paragraph

Review in Biochimica et biophysica acta. Reviews on cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 88 citations in OpenAlex.

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  14. Potential role for protein kinase D inhibitors in prostate cancer.Journal of molecular medicine (Berlin, Germany) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Adhiraj RoyDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15261, USA.
Jing YeDepartment of Anesthesiology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Fan DengDepartment of Cell Biology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.
Qiming Jane WangDepartment of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15261, USA. Electronic address: qjw1@pitt.edu.
Southern Medical University · CNUniversity of Pittsburgh · US

Funding

Development of small molecule inhibitors of protein kinase DR01CA142580 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WANG, QIMING JANE · 2010 to 2014
$1.5M
Novel long non-coding RNAs in neuronal survival in focal cerebral ischemiaR21NS096946 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI WANG, QIMING JANE · 2016 to 2017
$425k
NCI NIH HHS R01 CA142580NINDS NIH HHS R21 NS096946
6 · The paper itself

Abstract

Protein kinase D is a family of evolutionarily conserved serine/threonine kinases that belongs to the Ca

Indexed as

AnimalsDisease ProgressionHumansNeoplasmsNeovascularization, PathologicProtein Kinase CSignal TransductionProtein Kinase Cprotein kinase DCancerFunctionPKDRegulationSignaling mechanismsStructure

Identifiers

PMID28577984
PMCPMC5548606
OpenAlexW2620918492

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.