Evidence map›Paper›PMID 28600706›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2017

Effects of resistance exercise in prostate cancer patients: a meta-analysis.

M Keilani, T Hasenoehrl, L Baumann, R Ristl, M Schwarz, M Marhold, T Sedghi Komandj, R Crevenna

Abstract readMeta-AnalysisReview
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 15 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 15 syntheses or guidelines pooled it.

  1. Inclusivity in prostate cancer and exercise research: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  2. Effects of exercise during active surveillance for prostate cancer: A systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  3. Pooled it
  4. Does Androgen Deprivation for Prostate Cancer Affect Normal Adaptation to Resistance Exercise?International journal of environmental research and public health · 2022
    Pooled it
  5. Pooled it
  6. Pooled it
  7. High-intensity interval training in the prehabilitation of cancer patients-a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
  8. Physical exercise for bone health in men with prostate cancer receiving androgen deprivation therapy: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Pooled it
  9. Resistance exercise and breast cancer-related lymphedema-a systematic review update and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Pooled it
  10. Pooled it
  11. Pooled it
  12. Effects of exercise interventions on social and cognitive functioning of men with prostate cancer: a meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Impact of a Functional Intervention with Home Follow-Up on Respiratory Symptoms and Functionality in Oncology Patients: A Randomised Clinical Trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Trial
  17. Trial
  18. Trial
  19. Trial
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

M KeilaniDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Comprehensive Cancer Center, Waehringer Guertel 18-20, 1090, Vienna, Austria.
T HasenoehrlDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Comprehensive Cancer Center, Waehringer Guertel 18-20, 1090, Vienna, Austria.
L BaumannSection of Medical Statistics, CeMSIIS, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
R RistlSection of Medical Statistics, CeMSIIS, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
M SchwarzDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Comprehensive Cancer Center, Waehringer Guertel 18-20, 1090, Vienna, Austria.
M MarholdDepartment of Internal Medicine I/Oncology, Medical University of Vienna, Comprehensive Cancer Center, Waehringer Guertel 18-20, 1090, Vienna, Austria.
T Sedghi KomandjDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Comprehensive Cancer Center, Waehringer Guertel 18-20, 1090, Vienna, Austria.
R CrevennaDepartment of Physical Medicine, Rehabilitation and Occupational Medicine, Medical University of Vienna, Comprehensive Cancer Center, Waehringer Guertel 18-20, 1090, Vienna, Austria. richard.crevenna@meduniwien.ac.at.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of the present meta-analysis was to quantify effects of resistance exercise (RE) on physical performance and function, body composition, health-related quality of life (HRQoL), and fatigue in patients with prostate cancer.

methodsTrial data were obtained from the databases PubMed, MEDLINE, EMBASE, SCOPUS, and the Cochrane Library as of inception to 31st of December 2016. Thirty-two trials with 1199 patients were included. Results that were measured by using the same assessment method in five or more of the original studies were pooled in a meta-analysis.

resultsPooled studies showed significant improvements of muscular strength in the upper and lower body (95% CI [2.52, 7.97] kg; p < 0.001 and 95% CI [10.51, 45.88] kg; p = 0.008, respectively) after RE. Furthermore, significant improvements were seen for body composition (body fat percentage 95% CI [-0.79, -0.53] %; p < 0.001; lean body mass 95% CI [0.15, 1.84] %; p = 0.028; trunk fat mass 95% CI [-0.73, -0.08] kg; p = 0.024). Additionally, the improvement of the 400-m walk time was significant (95% CI [-21.55, -14.65] s; p < 0.001). Concerning fatigue and HRQoL, there were not sufficient data for analysis.

conclusionsRE seems to be a promising approach in order to counteract loss of muscle mass, muscle strength, and physical performance in patients suffering from prostate cancer and its treatment-related side effects. RE should play part in interdisciplinary cancer rehabilitation and care of this patient group. Nevertheless, further research should investigate RE further to determine which protocols are the most pragmatic, yet yielding best patient outcomes.

Indexed as

ExerciseExercise TherapyHumansMaleProstatic NeoplasmsQuality of LifeAndrogen deprivation therapyBody compositionMuscular strengthPhysical performanceProstate cancerResistance exercise

Identifiers

PMID28600706
PMCPMC5527087

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.