Evidence map›Paper›PMID 28602713›Full record

ReviewSeminars in immunology2017

Interplay between viruses and bacterial microbiota in cancer development.

Dariia Vyshenska, Khiem C Lam, Natalia Shulzhenko, Andrey Morgun

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. The Microbiota in Cancer: A Secondary Player or a Protagonist?Current issues in molecular biology · 2024
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Biology · 2021
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dariia VyshenskaCollege of Pharmacy, Oregon State University, 1601 SW Jefferson Way, Corvallis, OR 97331, USA.
Khiem C LamCollege of Pharmacy, Oregon State University, 1601 SW Jefferson Way, Corvallis, OR 97331, USA.
Natalia ShulzhenkoCollege of Veterinary Medicine, Oregon State University, 208 Dryden Hall, Corvallis, OR 97331, USA. Electronic address: natalia.shulzhenko@oregonstate.edu.
Andrey MorgunCollege of Pharmacy, Oregon State University, 1601 SW Jefferson Way, Corvallis, OR 97331, USA. Electronic address: Andriy.morgun@oregonstate.edu.
Oregon State University · US

Funding

Gut microbiota mediates the interplay between immunity and glucose metabolismR01DK103761 · NIDDK · OREGON STATE UNIVERSITY · PI SHULZHENKO, NATALIA · 2015 to 2019
$1.7M
Anti-IL-12p40 Treatment of CVID Enteropathy: Gene Expression/Microbiota AnalysisU01AI109695 · NIAID · OREGON STATE UNIVERSITY · PI MORGUN, ANDRIY · 2013 to 2015
$951k
NIAID NIH HHS U01 AI109695NIDDK NIH HHS R01 DK103761
6 · The paper itself

Abstract

During the last few decades we have become accustomed to the idea that viruses can cause tumors. It is much less considered and discussed, however, that most people infected with oncoviruses will never develop cancer. Therefore, the genetic and environmental factors that tip the scales from clearance of viral infection to development of cancer are currently an area of active investigation. Microbiota has recently emerged as a potentially critical factor that would affect this balance by increasing or decreasing the ability of viral infection to promote carcinogenesis. In this review, we provide a model of microbiome contribution to the development of oncogenic viral infections and viral associated cancers, give examples of this process in human tumors, and describe the challenges that prevent progress in the field as well as their potential solutions.

Indexed as

AnimalsCarcinogenesisGene-Environment InteractionHumansMicrobiotaNeoplasmsOncogenic VirusesViral LoadVirus DiseasesMicrobiomeMicrobiotaOncovirusTranskingdom interactionsVirus-associated cancer

Identifiers

PMID28602713
PMCPMC5685535
OpenAlexW2621883145

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.