Evidence map›Paper›PMID 28607813›Full record

ArticleBone research2017

Differential involvement of Wnt signaling in Bmp regulation of cancellous versus periosteal bone growth.

Guangxu He, Yu Shi, Joohyun Lim, Teresita Bellido, Jiangdong Ni, Fanxin Long

Open access · goldAbstract read
In one paragraph

Article in Bone research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. CRISPR-mediated conditional mutagenesis ofbioRxiv : the preprint server for biology · 2026
    Article
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  11. [Latest Research Findings on the Regulation of Bone Homeostasis by ALK3].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
    Review
  12. Article
  13. Krüppel-like factor 3 inhibition by mutated lncRNAThe Journal of experimental medicine · 2019
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Guangxu HeDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Hunan, China.
Yu ShiDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA.
Joohyun LimDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA.
Teresita BellidoDepartment of Anatomy and Cell Biology, Indiana University School of Medicine, Indianapolis, IN, USA.
Jiangdong NiDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Hunan, China.
Fanxin LongDepartment of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO, USA.
Washington University in St. Louis · USCentral South University · CNIndiana University School of Medicine

Funding

The Role of the Osteoblast Secretome in Bone FormationP30AR057235 · NIAMS · WASHINGTON UNIVERSITY · PI SWARNKAR, GAURAV · 2009 to 2018
$5.7M
Mechanisms of WNT Signaling In BoneR01AR060456 · NIAMS · WASHINGTON UNIVERSITY · PI LONG, FANXIN · 2010 to 2020
$4.0M
Notch Signaling and Bone FormationR01AR055923 · NIAMS · WASHINGTON UNIVERSITY · PI LONG, FANXIN · 2008 to 2017
$3.5M
NIAMS NIH HHS P30 AR057235NIAMS NIH HHS R01 AR055923NIAMS NIH HHS R01 AR060456
6 · The paper itself

Abstract

Bone morphogenetic proteins (Bmp) are well-known to induce bone formation following chondrogenesis, but the direct role of Bmp signaling in the osteoblast lineage is not completely understood. We have recently shown that deletion of the receptor Bmpr1a in the osteoblast lineage with

Identifiers

PMID28607813
PMCPMC5460368
OpenAlexW2621614025

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.