Evidence map›Paper›PMID 28623925›Full record

ArticleFluids and barriers of the CNS2017

Human jugular vein collapse in the upright posture: implications for postural intracranial pressure regulation.

Petter Holmlund, Elias Johansson, Sara Qvarlander, Anders Wåhlin, Khalid Ambarki, Lars-Owe D Koskinen, Jan Malm, Anders Eklund

Open access · goldAbstract read
In one paragraph

Article in Fluids and barriers of the CNS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Observational
  3. Effects of a Hyperbaric Normoxic Environment on the Retina and Choroid.Investigative ophthalmology & visual science · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Rebound Intracranial Hypertension.Current pain and headache reports · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Postural influence on intracranial fluid dynamics: an overview.Journal of physiological anthropology · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Petter HolmlundDepartment of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden. petter.holmlund@umu.se.ORCID http://orcid.org/0000-0002-1141-5143
Elias JohanssonDepartment of Pharmacology and Clinical Neuroscience, Umeå University, 901 87, Umeå, Sweden.
Sara QvarlanderDepartment of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden.
Anders WåhlinDepartment of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden.
Khalid AmbarkiDepartment of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden.
Lars-Owe D KoskinenDepartment of Pharmacology and Clinical Neuroscience, Umeå University, 901 87, Umeå, Sweden.
Jan MalmDepartment of Pharmacology and Clinical Neuroscience, Umeå University, 901 87, Umeå, Sweden.
Anders EklundDepartment of Radiation Sciences, Umeå University, 901 87, Umeå, Sweden.
Umeå University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntracranial pressure (ICP) is directly related to cranial dural venous pressure (P

methodsWe evaluated this potential mechanism in vivo by comparing predicted area to measured IJV area in healthy subjects. Seventeen healthy volunteers (age 45 ± 9 years) were examined using ultrasound to assess IJV area and flow velocity. Ultrasound measurements were performed in supine and sitting positions.

resultsIJV area was 94.5 mm

conclusionsThe agreement between predicted and measured IJV area in sitting supports the occurrence of a hydrostatic-viscous pressure balance in the IJVs, which would result in a constant pressure segment in these collapsed veins, corresponding to a zero transmural pressure. This balance could thus serve as the mechanism by which collapse of the IJVs regulates P

Indexed as

PostureAdultCentral Venous PressureFemaleHealthy VolunteersHumansJugular VeinsMaleMiddle AgedModels, BiologicalModels, CardiovascularShockUltrasonographyCollapseIntracranial pressureJugular veinPhysiologyPosture

Identifiers

PMID28623925
PMCPMC5473973
OpenAlexW2625042505

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.